Literature DB >> 18639680

Evaluating long-term results of modified Heller limited esophagomyotomy in children with esophageal achalasia.

George Vaos1, Leonidas Demetriou, Constantinos Velaoras, Constantinos Skondras.   

Abstract

BACKGROUND/
PURPOSE: Modified Heller esophagomyotomy has become the initial treatment of choice for esophageal achalasia in children. However, only limited and not objective data are currently available on the long-term results of modified Heller limited esophagomyotomy (LEM). This retrospective study was undertaken to objectively assess the long-term results of LEM in childhood esophageal achalasia.
METHODS: Medical records of 15 patients with a median age of 9.5 years (range, 6-13 years) who underwent an LEM without an antireflux procedure from January 1991 to December 2005 were reviewed. Clinical scores, barium esophagogram, flexible upper alimentary endoscopy, 24-hour esophageal pH monitoring, and esophageal manometry before and 0.5 to 15 years after surgery were analyzed.
RESULTS: An excellent to good outcome was observed in 14 (93.3%) patients. One patient (6.7%) required reoperation 8 months after surgery because of persistent dysphagia. The late barium esophagogram showed a significant decrease (from 4.2 +/- 0.95 to 2.4 +/- 1.1 cm, P < .01) of esophageal diameter, as compared with preoperative values. Only 1 patient had grade II esophagitis on flexible upper alimentary endoscopy. Twenty-four- hour esophageal pH monitoring showed an abnormal acid exposure in 1 patient. The late esophageal manometry showed a significant decrease (from 31.7 +/- 7.9 to 7.8 +/- 3.7 mm Hg; < .05) of lower esophageal sphincter (LES) pressure, and only insignificant increase (from 18.8 +/- 6.2 to 21.4 +/- 8.4 mm Hg; NS) of amplitude of esophageal contractions over preoperative values.
CONCLUSIONS: Transabdominal LEM without an antireflux procedure is an effective and safe treatment of esophageal achalasia in children because of its long-term high rate of symptoms relief and low incidence of postoperative complications, despite the lack of esophageal motility restoration to normal.

Entities:  

Mesh:

Year:  2008        PMID: 18639680     DOI: 10.1016/j.jpedsurg.2008.02.074

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  4 in total

1.  Achalasia: a rare cause of failure to thrive in children.

Authors:  Paul Gallagher; Farhana Sharif
Journal:  BMJ Case Rep       Date:  2009-05-21

2.  Outcomes of treatment of childhood achalasia.

Authors:  Constance W Lee; David W Kays; Mike K Chen; Saleem Islam
Journal:  J Pediatr Surg       Date:  2010-06       Impact factor: 2.545

3.  Long-term outcomes of Heller's myotomy and balloon dilatation in childhood achalasia.

Authors:  Efstratios Saliakellis; Nikhil Thapar; Derek Roebuck; Fernanda Cristofori; Kate Cross; Edward Kiely; Joseph Curry; Keith Lindley; Osvaldo Borrelli
Journal:  Eur J Pediatr       Date:  2017-05-23       Impact factor: 3.183

4.  Diagnosis, misdiagnosis, and associated diseases of achalasia in children and adolescents: a twelve-year single center experience.

Authors:  Cristiane Hallal; Carlos O Kieling; Daltro L Nunes; Cristina T Ferreira; Guilherme Peterson; Sérgio G S Barros; Cristina A Arruda; José C Fraga; Helena A S Goldani
Journal:  Pediatr Surg Int       Date:  2012-11-08       Impact factor: 1.827

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.