PURPOSE: We determined the influence of temperature on the minimal stimulation frequency required to block pudendal nerve conduction. MATERIALS AND METHODS: The pudendal nerve block induced by high frequency, biphasic electrical current was investigated at different temperatures using cats under alpha-chloralose anesthesia. Urethral pressure was measured to indicate pudendal nerve activation or block. RESULTS: As stimulation frequency was increased above a frequency threshold, the urethral pressure response was decreased and the pudendal nerve was blocked. The minimal stimulation frequency required to block the pudendal nerve was decreased from 6 to 4 kHz as the temperature was decreased from 37C to 15C. At a 4 kHz frequency the maximal temperature below which the pudendal nerve could be blocked was 24.5C. CONCLUSIONS: To block pudendal nerve conduction at body temperature (37C) the stimulation frequency must be greater than 6 kHz. This study provides a practical guide for blocking the pudendal nerves to restore efficient voiding after spinal cord injury.
PURPOSE: We determined the influence of temperature on the minimal stimulation frequency required to block pudendal nerve conduction. MATERIALS AND METHODS: The pudendal nerve block induced by high frequency, biphasic electrical current was investigated at different temperatures using cats under alpha-chloralose anesthesia. Urethral pressure was measured to indicate pudendal nerve activation or block. RESULTS: As stimulation frequency was increased above a frequency threshold, the urethral pressure response was decreased and the pudendal nerve was blocked. The minimal stimulation frequency required to block the pudendal nerve was decreased from 6 to 4 kHz as the temperature was decreased from 37C to 15C. At a 4 kHz frequency the maximal temperature below which the pudendal nerve could be blocked was 24.5C. CONCLUSIONS: To block pudendal nerve conduction at body temperature (37C) the stimulation frequency must be greater than 6 kHz. This study provides a practical guide for blocking the pudendal nerves to restore efficient voiding after spinal cord injury.
Authors: Jialiang Chen; Yihua Zhong; Jicheng Wang; Bing Shen; Jonathan Beckel; William C de Groat; Changfeng Tai Journal: Neuromodulation Date: 2021-12-18
Authors: Yihua Zhong; Jicheng Wang; Jonathan Beckel; William C de Groat; Changfeng Tai Journal: J Comput Neurosci Date: 2021-11-20 Impact factor: 1.453
Authors: David Martín-Caro Álvarez; Diego Serrano-Muñoz; Juan José Fernández-Pérez; Julio Gómez-Soriano; Juan Avendaño-Coy Journal: J Clin Med Date: 2022-03-25 Impact factor: 4.241