Literature DB >> 18637510

Subversion of cell cycle regulatory pathways.

V Sanchez1, D H Spector.   

Abstract

Human cytomegalovirus (HCMV) has evolved numerous strategies to commandeer the host cell for producing viral progeny. The virus manipulates host cell cycle pathways from the early stages of infection to stimulate viral DNA replication at the expense of cellular DNA synthesis. At the same time, cell cycle checkpoints are by-passed, preventing apoptosis and allowing sufficient time for the assembly of infectious virus.

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Year:  2008        PMID: 18637510     DOI: 10.1007/978-3-540-77349-8_14

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN: 0070-217X            Impact factor:   4.291


  37 in total

1.  Enhancerless cytomegalovirus is capable of establishing a low-level maintenance infection in severely immunodeficient host tissues but fails in exponential growth.

Authors:  Jürgen Podlech; Rares Pintea; Kai A Kropp; Annette Fink; Niels A W Lemmermann; Katja C Erlach; Elena Isern; Ana Angulo; Peter Ghazal; Matthias J Reddehase
Journal:  J Virol       Date:  2010-04-07       Impact factor: 5.103

2.  Human cytomegalovirus early protein pUL21a promotes efficient viral DNA synthesis and the late accumulation of immediate-early transcripts.

Authors:  Anthony R Fehr; Dong Yu
Journal:  J Virol       Date:  2010-11-03       Impact factor: 5.103

3.  The essential role of guinea pig cytomegalovirus (GPCMV) IE1 and IE2 homologs in viral replication and IE1-mediated ND10 targeting.

Authors:  Julia Hornig; K Yeon Choi; Alistair McGregor
Journal:  Virology       Date:  2017-02-10       Impact factor: 3.616

Review 4.  The roles of viruses in brain tumor initiation and oncomodulation.

Authors:  Alexander Kofman; Lucasz Marcinkiewicz; Evan Dupart; Anton Lyshchev; Boris Martynov; Anatolii Ryndin; Elena Kotelevskaya; Jay Brown; David Schiff; Roger Abounader
Journal:  J Neurooncol       Date:  2011-07-01       Impact factor: 4.130

5.  Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesis.

Authors:  Michael Melnick; George Abichaker; Khine Htet; Parish Sedghizadeh; Tina Jaskoll
Journal:  Exp Mol Pathol       Date:  2011-05-01       Impact factor: 3.362

Review 6.  Ubiquitin-independent proteasomal degradation during oncogenic viral infections.

Authors:  Jiwon Hwang; Laura Winkler; Robert F Kalejta
Journal:  Biochim Biophys Acta       Date:  2011-06-06

7.  Inhibition of cellular STAT3 synergizes with the cytomegalovirus kinase inhibitor maribavir to disrupt infection.

Authors:  Justin M Reitsma; Scott S Terhune
Journal:  Antiviral Res       Date:  2013-09-23       Impact factor: 5.970

8.  Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.

Authors:  Zhikang Qian; Van Leung-Pineda; Baoqin Xuan; Helen Piwnica-Worms; Dong Yu
Journal:  PLoS Pathog       Date:  2010-03-19       Impact factor: 6.823

9.  Human cytomegalovirus infection causes premature and abnormal differentiation of human neural progenitor cells.

Authors:  Min Hua Luo; Holger Hannemann; Amit S Kulkarni; Philip H Schwartz; John M O'Dowd; Elizabeth A Fortunato
Journal:  J Virol       Date:  2010-01-13       Impact factor: 5.103

Review 10.  The story of human cytomegalovirus and cancer: increasing evidence and open questions.

Authors:  Martin Michaelis; Hans W Doerr; Jindrich Cinatl
Journal:  Neoplasia       Date:  2009-01       Impact factor: 5.715

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