Literature DB >> 18637055

Mechanism for gastric cancer development by Helicobacter pylori infection.

Tsutomu Chiba1, Hiroyuki Marusawa, Hiroshi Seno, Norihiko Watanabe.   

Abstract

Helicobacter pylori (H. pylori) infection plays a crucial role in the development of gastric cancer. There are two major pathways for the development of gastric cancer by H. pylori infection: the indirect action of H. pylori on gastric epithelial cells through inflammation, and the direct action of the bacteria on epithelial cells through the induction of protein modulation and gene mutation. Both pathways work together to promote gastric carcinogenesis.

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Year:  2008        PMID: 18637055     DOI: 10.1111/j.1440-1746.2008.05472.x

Source DB:  PubMed          Journal:  J Gastroenterol Hepatol        ISSN: 0815-9319            Impact factor:   4.029


  26 in total

1.  Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers.

Authors:  Yoko Endo; Hiroyuki Marusawa; Tsutomu Chiba
Journal:  J Gastroenterol       Date:  2010-09-28       Impact factor: 7.527

Review 2.  Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention.

Authors:  Parisa Karimi; Farhad Islami; Sharmila Anandasabapathy; Neal D Freedman; Farin Kamangar
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2014-03-11       Impact factor: 4.254

3.  Comparison of the Clinicopathological Characteristics and Genetic Alterations Between Patients with Gastric Cancer with or Without Helicobacter pylori Infection.

Authors:  Wen-Liang Fang; Kuo-Hung Huang; Shih-Ching Chang; Chien-Hsing Lin; Ming-Huang Chen; Yee Chao; Su-Shun Lo; Anna Fen-Yau Li; Chew-Wun Wu; Yi-Ming Shyr
Journal:  Oncologist       Date:  2019-02-22

4.  Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine?

Authors:  Hilda Wong; Thomas Yau
Journal:  Oncologist       Date:  2012-02-14

Review 5.  Role of the tumor microenvironment in the pathogenesis of gastric carcinoma.

Authors:  Hye Won Chung; Jong-Baeck Lim
Journal:  World J Gastroenterol       Date:  2014-02-21       Impact factor: 5.742

Review 6.  Gastrin, inflammation, and carcinogenesis.

Authors:  Celia Chao; Mark R Hellmich
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2010-02       Impact factor: 3.243

7.  Effects of radix curcumae-derived diterpenoid C on Helicobacter pylori-induced inflammation and nuclear factor kappa B signal pathways.

Authors:  Xuan Huang; Bin Lv; Shuo Zhang; Qun Dai; Bing-Bing Chen; Li-Na Meng
Journal:  World J Gastroenterol       Date:  2013-08-21       Impact factor: 5.742

Review 8.  A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction.

Authors:  Tsutomu Chiba; Hiroyuki Marusawa
Journal:  J Mol Med (Berl)       Date:  2009-10       Impact factor: 4.599

9.  Long intergenic noncoding RNA00265 promotes proliferation of gastric cancer via the microRNA-144-3p/Chromobox 4 axis.

Authors:  Zengxi Yang; Xi OuYang; Liang Zheng; Lizhen Dai; Wenjuan Luo
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

Review 10.  Nature meets nurture: molecular genetics of gastric cancer.

Authors:  Anya N Milne; F Carneiro; C O'Morain; G J A Offerhaus
Journal:  Hum Genet       Date:  2009-08-06       Impact factor: 4.132

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