Literature DB >> 18635572

The protein information and property explorer: an easy-to-use, rich-client web application for the management and functional analysis of proteomic data.

H Ramos1, P Shannon, R Aebersold.   

Abstract

MOTIVATION: Mass spectrometry experiments in the field of proteomics produce lists containing tens to thousands of identified proteins. With the protein information and property explorer (PIPE), the biologist can acquire functional annotations for these proteins and explore the enrichment of the list, or fraction thereof, with respect to functional classes. These protein lists may be saved for access at a later time or different location. The PIPE is interoperable with the Firegoose and the Gaggle, permitting wide-ranging data exploration and analysis. The PIPE is a rich-client web application which uses AJAX capabilities provided by the Google Web Toolkit, and server-side data storage using Hibernate. AVAILABILITY: http://pipe.systemsbiology.net.

Mesh:

Year:  2008        PMID: 18635572      PMCID: PMC2638980          DOI: 10.1093/bioinformatics/btn363

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  5 in total

1.  Cytoscape: a software environment for integrated models of biomolecular interaction networks.

Authors:  Paul Shannon; Andrew Markiel; Owen Ozier; Nitin S Baliga; Jonathan T Wang; Daniel Ramage; Nada Amin; Benno Schwikowski; Trey Ideker
Journal:  Genome Res       Date:  2003-11       Impact factor: 9.043

2.  Using GOstats to test gene lists for GO term association.

Authors:  S Falcon; R Gentleman
Journal:  Bioinformatics       Date:  2006-11-10       Impact factor: 6.937

3.  The Gaggle: an open-source software system for integrating bioinformatics software and data sources.

Authors:  Paul T Shannon; David J Reiss; Richard Bonneau; Nitin S Baliga
Journal:  BMC Bioinformatics       Date:  2006-03-28       Impact factor: 3.169

4.  A uniform proteomics MS/MS analysis platform utilizing open XML file formats.

Authors:  Andrew Keller; Jimmy Eng; Ning Zhang; Xiao-jun Li; Ruedi Aebersold
Journal:  Mol Syst Biol       Date:  2005-08-02       Impact factor: 11.429

5.  The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications.

Authors:  J Christopher Bare; Paul T Shannon; Amy K Schmid; Nitin S Baliga
Journal:  BMC Bioinformatics       Date:  2007-11-19       Impact factor: 3.169

  5 in total
  19 in total

1.  The Protein Information and Property Explorer 2: gaggle-like exploration of biological proteomic data within one webpage.

Authors:  Hector Ramos; Paul Shannon; Mi-Youn Brusniak; Ulrike Kusebauch; Robert L Moritz; Ruedi Aebersold
Journal:  Proteomics       Date:  2010-12-06       Impact factor: 3.984

Review 2.  Network inference and network response identification: moving genome-scale data to the next level of biological discovery.

Authors:  Diogo F T Veiga; Bhaskar Dutta; Gábor Balázsi
Journal:  Mol Biosyst       Date:  2009-12-11

3.  Software tool for researching annotations of proteins: open-source protein annotation software with data visualization.

Authors:  Vivek N Bhatia; David H Perlman; Catherine E Costello; Mark E McComb
Journal:  Anal Chem       Date:  2009-12-01       Impact factor: 6.986

4.  Integrated phosphoproteomics analysis of a signaling network governing nutrient response and peroxisome induction.

Authors:  Ramsey A Saleem; Richard S Rogers; Alexander V Ratushny; David J Dilworth; Paul T Shannon; David Shteynberg; Yakun Wan; Robert L Moritz; Alexey I Nesvizhskii; Richard A Rachubinski; John D Aitchison
Journal:  Mol Cell Proteomics       Date:  2010-04-15       Impact factor: 5.911

5.  Glycocapture-assisted global quantitative proteomics (gagQP) reveals multiorgan responses in serum toxicoproteome.

Authors:  Bingyun Sun; Angelita G Utleg; Zhiyuan Hu; Shizhen Qin; Andrew Keller; Cynthia Lorang; Li Gray; Amy Brightman; Denis Lee; Vinita M Alexander; Jeffrey A Ranish; Robert L Moritz; Leroy Hood
Journal:  J Proteome Res       Date:  2013-04-11       Impact factor: 4.466

6.  Techniques for accurate protein identification in shotgun proteomic studies of human, mouse, bovine, and chicken lenses.

Authors:  Phillip A Wilmarth; Michael A Riviere; Larry L David
Journal:  J Ocul Biol Dis Infor       Date:  2009-12-12

7.  A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products.

Authors:  Ulrich auf dem Keller; Anna Prudova; Magda Gioia; Georgina S Butler; Christopher M Overall
Journal:  Mol Cell Proteomics       Date:  2010-03-20       Impact factor: 5.911

8.  Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics.

Authors:  Anna Prudova; Ulrich auf dem Keller; Georgina S Butler; Christopher M Overall
Journal:  Mol Cell Proteomics       Date:  2010-03-20       Impact factor: 5.911

9.  ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.

Authors:  Gabriela Bindea; Bernhard Mlecnik; Hubert Hackl; Pornpimol Charoentong; Marie Tosolini; Amos Kirilovsky; Wolf-Herman Fridman; Franck Pagès; Zlatko Trajanoski; Jérôme Galon
Journal:  Bioinformatics       Date:  2009-02-23       Impact factor: 6.937

10.  The membrane proteome of the mouse lens fiber cell.

Authors:  Steven Bassnett; Phillip A Wilmarth; Larry L David
Journal:  Mol Vis       Date:  2009-11-24       Impact factor: 2.367

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