BACKGROUND: Agitation is associated with failure of noninvasive ventilation (NIV). We investigated the effect of dexmedetomidine in patients with NIV. METHODS: This was a prospective clinical investigation in an intensive care unit. Dexmedetomidine was infused in 10 patients in whom NIV was difficult because of agitation. RESULTS: Ramsay and Richmond Agitation-Sedation Scale scores were maintained at 2.94 +/- 0.94 and -1.23 +/- 1.30, respectively. All patients were successfully weaned from NIV, and the respiratory state was not worsened. CONCLUSION: This study shows that dexmedetomidine is an effective sedative drug for patients with NIV.
BACKGROUND:Agitation is associated with failure of noninvasive ventilation (NIV). We investigated the effect of dexmedetomidine in patients with NIV. METHODS: This was a prospective clinical investigation in an intensive care unit. Dexmedetomidine was infused in 10 patients in whom NIV was difficult because of agitation. RESULTS: Ramsay and Richmond Agitation-Sedation Scale scores were maintained at 2.94 +/- 0.94 and -1.23 +/- 1.30, respectively. All patients were successfully weaned from NIV, and the respiratory state was not worsened. CONCLUSION: This study shows that dexmedetomidine is an effective sedative drug for patients with NIV.
Authors: Alfonso Muriel; Oscar Peñuelas; Fernando Frutos-Vivar; Alejandro C Arroliga; Victor Abraira; Arnaud W Thille; Laurent Brochard; Nicolás Nin; Andrew R Davies; Pravin Amin; Bin Du; Konstantinos Raymondos; Fernando Rios; Damian A Violi; Salvatore M Maggiore; Marco Antonio Soares; Marco González; Fekri Abroug; Hans-Henrik Bülow; Javier Hurtado; Michael A Kuiper; Rui P Moreno; Amine Ali Zeggwagh; Asisclo J Villagómez; Manuel Jibaja; Luis Soto; Gabriel D'Empaire; Dimitrios Matamis; Younsuck Koh; Antonio Anzueto; Niall D Ferguson; Andrés Esteban Journal: Intensive Care Med Date: 2015-05-14 Impact factor: 17.440
Authors: Noorizan Abd Aziz; Mui Ching Chue; Chow Yen Yong; Yahaya Hassan; Ahmed Awaisu; Jahizah Hassan; Mohd Hamzah Kamarulzaman Journal: Int J Clin Pharm Date: 2011-01-28