| Literature DB >> 18635000 |
Abstract
Aptamers, sometimes termed "chemical antibodies," have been engineered into multimerized versions for therapeutic application. The groups of Gilboa and Sullenger now report the development of a bivalent aptamer-molecular device as a receptor agonist that has the same functional properties, but stronger avidity than a corresponding antibody.Mesh:
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Year: 2008 PMID: 18635000 DOI: 10.1016/j.chembiol.2008.07.004
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521