Single-step apical barrier placement in immature teeth using mineral trioxide aggregate and management of periapical inflammatory lesion using platelet-rich plasma and hydroxyapatite.

We present here a case report of a tooth with an immature root with a large periapical lesion. The open apex was managed by placing an apical barrier using mineral trioxide aggregate, and the periapical lesion was treated surgically. A combination of platelet-rich plasma (PRP) and hydroxyapatite graft (HA) was used to achieve faster healing of the periapical lesion. The case was followed up for 11 months. The indications and advantages of apical barrier placement, periapical surgery, and the role of PRP and HA in postsurgical healing are discussed.