Literature DB >> 18631956

2008 Alzheimer's disease facts and figures.

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Abstract

Alzheimer's disease is the seventh leading cause of all deaths in the United States and the fifth leading cause of death in Americans older than the age of 65 years. More than 5 million Americans are estimated to have Alzheimer's disease. Every 71 seconds someone in America develops Alzheimer's disease; by 2050 it is expected to occur every 33 seconds. During the coming decades, baby boomers are projected to add 10 million people to these numbers. By 2050, the incidence of Alzheimer's disease is expected to approach nearly a million people per year, with a total estimated prevalence of 11 to 16 million persons. Significant cost implications related to Alzheimer's disease and other dementias include an estimated $148 billion annually in direct (Medicare/Medicaid) and indirect (eg, caregiver lost wages and out-of-pocket expenses, decreased business productivity) costs. Not included in these figures are the estimated 10 million caregivers who annually provide $89 billion in unpaid services to individuals with Alzheimer's disease. This report provides information to increase understanding of the public health impact of Alzheimer's disease, including incidence and prevalence, mortality, lifetime risks, costs, and impact on family caregivers.

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Year:  2008        PMID: 18631956     DOI: 10.1016/j.jalz.2008.02.005

Source DB:  PubMed          Journal:  Alzheimers Dement        ISSN: 1552-5260            Impact factor:   21.566


  64 in total

1.  Mary S. Easton Center of Alzheimer's Disease Research at UCLA: advancing the therapeutic imperative.

Authors:  Jeffrey L Cummings; John Ringman; Karen Metz
Journal:  J Alzheimers Dis       Date:  2010       Impact factor: 4.472

2.  Therapy for Alzheimer's Disease: How Effective are Current Treatments?

Authors:  Krista L Lanctôt; Ryan D Rajaram; Nathan Herrmann
Journal:  Ther Adv Neurol Disord       Date:  2009-05       Impact factor: 6.570

3.  Design of comprehensive Alzheimer's disease centers to address unmet national needs.

Authors:  John Q Trojanowski; Steven E Arnold; Jason H Karlawish; Kurt Brunden; Mark Cary; Christos Davatzikos; John Detre; Glen Gaulton; Murray Grossman; Howard Hurtig; Kathryn Jedrziewski; Leo McCluskey; Mary Naylor; Daniel Polsky; Gerard D Schellenberg; Andrew Siderowf; Leslie M Shaw; Vivianna Van Deerlin; Li-San Wang; Rachel Werner; Sharon X Xie; Virginia M-Y Lee
Journal:  Alzheimers Dement       Date:  2010-03       Impact factor: 21.566

4.  Caregiver-recipient closeness and symptom progression in Alzheimer disease. The Cache County Dementia Progression Study.

Authors:  Maria C Norton; Kathleen W Piercy; Peter V Rabins; Robert C Green; John C S Breitner; Truls Ostbye; Christopher Corcoran; Kathleen A Welsh-Bohmer; Constantine G Lyketsos; Joann T Tschanz
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2009-06-29       Impact factor: 4.077

5.  Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice.

Authors:  Remi Dosunmu; Jinfang Wu; Lina Adwan; Bryan Maloney; Md Riyaz Basha; Christopher A McPherson; G Jean Harry; Deborah C Rice; Nasser H Zawia; Debomoy K Lahiri
Journal:  J Alzheimers Dis       Date:  2009       Impact factor: 4.472

6.  Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimer's disease and mild cognitive impairment: implications for progression of AD.

Authors:  Joshua B Owen; Fabio Di Domenico; Rukhsana Sultana; Marzia Perluigi; Chiara Cini; William M Pierce; D Allan Butterfield
Journal:  J Proteome Res       Date:  2009-02       Impact factor: 4.466

7.  Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging.

Authors:  Wolfgang Lieb; Alexa S Beiser; Ramachandran S Vasan; Zaldy S Tan; Rhoda Au; Tamara B Harris; Ronenn Roubenoff; Sanford Auerbach; Charles DeCarli; Philip A Wolf; Sudha Seshadri
Journal:  JAMA       Date:  2009-12-16       Impact factor: 56.272

8.  Effect of study partner on the conduct of Alzheimer disease clinical trials.

Authors:  Joshua D Grill; Rema Raman; Karin Ernstrom; Paul Aisen; Jason Karlawish
Journal:  Neurology       Date:  2012-12-19       Impact factor: 9.910

Review 9.  Understanding the molecular basis of Alzheimer's disease using a Caenorhabditis elegans model system.

Authors:  Collin Y Ewald; Chris Li
Journal:  Brain Struct Funct       Date:  2009-12-11       Impact factor: 3.270

10.  Effects of family history and apolipoprotein E epsilon4 status on cognitive decline in the absence of Alzheimer dementia: the Cache County Study.

Authors:  Kathleen M Hayden; Peter P Zandi; Nancy A West; Joann T Tschanz; Maria C Norton; Chris Corcoran; John C S Breitner; Kathleen A Welsh-Bohmer
Journal:  Arch Neurol       Date:  2009-11
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