Literature DB >> 18631314

The outcomes and outpatient costs of different models of antiretroviral treatment delivery in South Africa.

Sydney Rosen1, Lawrence Long, Ian Sanne.   

Abstract

OBJECTIVE: Estimate the average outpatient cost per patient in care and responding to treatment 1 year after initiation of antiretroviral therapy (ART) under different models of treatment delivery in South Africa.
METHODS: At each site, medical records for a sample patients of were reviewed 1 year after ART initiation. Each subject was assigned to one outcome category: in care and responding (IC); in care but not responding (NR); or no longer in care at study site (NIC). Average cost per outcomes category was estimated based on resource utilisation.
RESULTS: Site 1 was an urban public hospital; Site 2 a programme that contracts private general practitioners; Site 3 a rural non-governmental (NGO) AIDS clinic; and Site 4 a peri-urban NGO primary care clinic. At month 12, IC, NR and NIC rates were 67%, 7% and 26% (Site 1); 52%, 3%, and 45% (Site 2); 63%, 9% and 28% (Site 3); and 76%, 11%, and 13% (Site 4). The average outpatient cost per patient initiated was $756 (Site 1), $896 (Site 2), $932 (Site 3) and $1,126 (Site 4). When all costs and all outcomes were taken into account, the average cost to produce an IC patient was $1,128 (Site 1), $1,723 (Site 2), $1,480 (Site 3), and $1,482 (Site 4).
CONCLUSION: If all ART patients remain in care and responding, total costs will increase but the average cost to produce an IC patient will fall. The cost per ART patient treated varies moderately among sites. Cost differences increase markedly when patient outcomes are taken into account.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18631314     DOI: 10.1111/j.1365-3156.2008.02114.x

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  48 in total

1.  Increases in adult life expectancy in rural South Africa: valuing the scale-up of HIV treatment.

Authors:  Jacob Bor; Abraham J Herbst; Marie-Louise Newell; Till Bärnighausen
Journal:  Science       Date:  2013-02-22       Impact factor: 47.728

Review 2.  The state of health economic research in South Africa: a systematic review.

Authors:  Paul Gavaza; Karen L Rascati; Abiola O Oladapo; Star Khoza
Journal:  Pharmacoeconomics       Date:  2012-10-01       Impact factor: 4.981

Review 3.  Unit costs for delivery of antiretroviral treatment and prevention of mother-to-child transmission of HIV: a systematic review for low- and middle-income countries.

Authors:  Omar Galárraga; Veronika J Wirtz; Alejandro Figueroa-Lara; Yared Santa-Ana-Tellez; Ibrahima Coulibaly; Kirsi Viisainen; Antonieta Medina-Lara; Eline L Korenromp
Journal:  Pharmacoeconomics       Date:  2011-07       Impact factor: 4.981

4.  Superior outcomes and lower outpatient costs with scale-up of antiretroviral therapy at the GHESKIO clinic in Port-au-Prince, Haiti.

Authors:  Cynthia Riviere; Elizabeth Faust; Thane Miller; Eduard J Beck; Elaine Baruwa; Patrice Severe; Karine Severe; Claudia Thomas Riché; Rachelle Cassagnol; Sidney Atwood; Morgan Esperance; Lauren Webster; Pierre Cremieux; Jean W Pape; Serena P Koenig
Journal:  J Acquir Immune Defic Syndr       Date:  2014-08-01       Impact factor: 3.731

5.  Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa.

Authors:  Matthew P Fox; Mhairi Maskew; A Patrick MacPhail; Lawrence Long; Alana T Brennan; Daniel Westreich; William B MacLeod; Pappie Majuba; Ian M Sanne
Journal:  Int J Epidemiol       Date:  2012-03-20       Impact factor: 7.196

Review 6.  Is there scope for cost savings and efficiency gains in HIV services? A systematic review of the evidence from low- and middle-income countries.

Authors:  Mariana Siapka; Michelle Remme; Carol Dayo Obure; Claudia B Maier; Karl L Dehne; Anna Vassall
Journal:  Bull World Health Organ       Date:  2014-04-01       Impact factor: 9.408

7.  Financing equitable access to antiretroviral treatment in South Africa.

Authors:  Susan Cleary; Di McIntyre
Journal:  BMC Health Serv Res       Date:  2010-07-02       Impact factor: 2.655

Review 8.  Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007-2009: systematic review.

Authors:  Matthew P Fox; Sydney Rosen
Journal:  Trop Med Int Health       Date:  2010-06       Impact factor: 2.622

9.  Secular trends in pediatric antiretroviral treatment programs in rural and urban Zambia: a retrospective cohort study.

Authors:  Catherine G Sutcliffe; Carolyn Bolton-Moore; Janneke H van Dijk; Matt Cotham; Bushimbwa Tambatamba; William J Moss
Journal:  BMC Pediatr       Date:  2010-07-30       Impact factor: 2.125

10.  Early and late direct costs in a Southern African antiretroviral treatment programme: a retrospective cohort analysis.

Authors:  Rory Leisegang; Susan Cleary; Michael Hislop; Alistair Davidse; Leon Regensberg; Francesca Little; Gary Maartens
Journal:  PLoS Med       Date:  2009-12-01       Impact factor: 11.069

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.