| Literature DB >> 18630880 |
Gopal Sirasani1, Tapas Paul, Rodrigo B Andrade.
Abstract
The cytotoxic natural product (+)-crocacin C ( 1) has been synthesized in 10 linear steps from commercially available Evans' chiral propionimide in 5% overall yield (8 steps from Evans' chiral dipropionate synthon). No protecting groups were utilized.Entities:
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Year: 2008 PMID： 18630880 DOI： 10.1021/jo800906p
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354