BACKGROUND: Only a few studies have reported any prognostic impact of the preoperative hemoglobin level itself in resectable non-small cell lung cancer (NSCLC). The survival impact of preoperative hemoglobin level and the relationship between hemoglobin and serum CEA level were investigated. PATIENTS AND METHODS: Two hundred and forty consecutive NSCLC patients were reviewed retrospectively. RESULTS: The 5-year survival of patients with low and those with a normal hemoglobin level was 42.99% and 73.47%, respectively. Both univariate and multivariate analyses indicated the independent prognostic impact of the hemoglobin level. The result for stage I patients was identical. Patients with normal hemoglobin could be subdivided into 2 groups based on their serum CEA level; the 5-year survival of patients with normal and those with elevated CEA was 81.72% and 57.24%, respectively. CONCLUSION: The preoperative hemoglobin level was a prognostic factor for NSCLC patients. The combined use of hemoglobin and CEA levels might be useful to predict the prognosis of patients.
BACKGROUND: Only a few studies have reported any prognostic impact of the preoperative hemoglobin level itself in resectable non-small cell lung cancer (NSCLC). The survival impact of preoperative hemoglobin level and the relationship between hemoglobin and serum CEA level were investigated. PATIENTS AND METHODS: Two hundred and forty consecutive NSCLCpatients were reviewed retrospectively. RESULTS: The 5-year survival of patients with low and those with a normal hemoglobin level was 42.99% and 73.47%, respectively. Both univariate and multivariate analyses indicated the independent prognostic impact of the hemoglobin level. The result for stage I patients was identical. Patients with normal hemoglobin could be subdivided into 2 groups based on their serum CEA level; the 5-year survival of patients with normal and those with elevated CEA was 81.72% and 57.24%, respectively. CONCLUSION: The preoperative hemoglobin level was a prognostic factor for NSCLCpatients. The combined use of hemoglobin and CEA levels might be useful to predict the prognosis of patients.
Authors: P Kelly; V Appleyard; K Murray; F Paulin; D Lamont; L Baker; S Suttie; D Exon; A Thompson Journal: Br J Cancer Date: 2010-06-15 Impact factor: 7.640
Authors: Juan P Cata; Cristina Gutierrez; Reza J Mehran; David Rice; Joseph Nates; Lei Feng; Andrea Rodriguez-Restrepo; Fernando Martinez; Gabriel Mena; Vijaya Gottumukkala Journal: Cancer Cell Microenviron Date: 2016
Authors: Georg Holgersson; Martin Sandelin; Even Hoye; Stefan Bergström; Roger Henriksson; Simon Ekman; Jan Nyman; Martin Helsing; Signe Friesland; Margareta Holgersson; Kristina Lamberg Lundström; Christer Janson; Elisabet Birath; Charlotte Mörth; Thomas Blystad; Sven-Börje Ewers; Britta Löden; Michael Bergqvist Journal: Med Oncol Date: 2012-05-08 Impact factor: 3.064