Literature DB >> 18629466

Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications.

Sabine Hombach-Klonisch1, Soumya Panigrahi, Iran Rashedi, Anja Seifert, Esteban Alberti, Paola Pocar, Maciej Kurpisz, Klaus Schulze-Osthoff, Andrzej Mackiewicz, Marek Los.   

Abstract

Stem cells are self-renewing multipotent progenitors with the broadest developmental potential in a given tissue at a given time. Normal stem cells in the adult organism are responsible for renewal and repair of aged or damaged tissue. Adult stem cells are present in virtually all tissues and during most stages of development. In this review, we introduce the reader to the basic information about the field. We describe selected stem cell isolation techniques and stem cell markers for various stem cell populations. These include makers for endothelial progenitor cells (CD146/MCAM/MUC18/S-endo-1, CD34, CD133/prominin, Tie-2, Flk1/KD/VEGFR2), hematopoietic stem cells (CD34, CD117/c-Kit, Sca1), mesenchymal stem cells (CD146/MCAM/MUC18/S-endo-1, STRO-1, Thy-1), neural stem cells (CD133/prominin, nestin, NCAM), mammary stem cells (CD24, CD29, Sca1), and intestinal stem cells (NCAM, CD34, Thy-1, CD117/c-Kit, Flt-3). Separate section provides a concise summary of recent clinical trials involving stem cells directed towards improvement of a damaged myocardium. In the last part of the review, we reflect on the field and on future developments.

Entities:  

Mesh：

Year:  2008        PMID： 18629466      PMCID： PMC2954191          DOI： 10.1007/s00109-008-0383-6

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  131 in total

Review 1.  Plasticity, niches, and the use of stem cells.

Authors:  Robert Y L Tsai; Raja Kittappa; Ronald D G McKay
Journal:  Dev Cell       Date:  2002-06       Impact factor: 12.270

2.  Dedifferentiation of lineage-committed cells by a small molecule.

Authors:  Shuibing Chen; Qisheng Zhang; Xu Wu; Peter G Schultz; Sheng Ding
Journal:  J Am Chem Soc       Date:  2004-01-21       Impact factor: 15.419

Review 3.  Metamorphosis from bone marrow derived primitive stem cells to functional liver cells.

Authors:  Yoon-Young Jang; Saul J Sharkis
Journal:  Cell Cycle       Date:  2004-08-09       Impact factor: 4.534

4.  Detection and characterization of primitive malignant and normal progenitors in patients with acute myelogenous leukemia using long-term coculture with supportive feeder layers and cytokines.

Authors:  L E Ailles; B Gerhard; D E Hogge
Journal:  Blood       Date:  1997-10-01       Impact factor: 22.113

Review 5.  Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells.

Authors:  M Kucia; R Reca; V R Jala; B Dawn; J Ratajczak; M Z Ratajczak
Journal:  Leukemia       Date:  2005-07       Impact factor: 11.528

Review 6.  Regenerating the heart.

Authors:  Michael A Laflamme; Charles E Murry
Journal:  Nat Biotechnol       Date:  2005-07       Impact factor: 54.908

7.  Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells.

Authors:  K A Jackson; S M Majka; H Wang; J Pocius; C J Hartley; M W Majesky; M L Entman; L H Michael; K K Hirschi; M A Goodell
Journal:  J Clin Invest       Date:  2001-06       Impact factor: 14.808

8.  Liver from bone marrow in humans.

Authors:  N D Theise; M Nimmakayalu; R Gardner; P B Illei; G Morgan; L Teperman; O Henegariu; D S Krause
Journal:  Hepatology       Date:  2000-07       Impact factor: 17.425

9.  Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: phase I clinical study with 12 months of follow-up.

Authors:  Tomasz Siminiak; Ryszard Kalawski; Dorota Fiszer; Olga Jerzykowska; Janusz Rzeźniczak; Natalia Rozwadowska; Maciej Kurpisz
Journal:  Am Heart J       Date:  2004-09       Impact factor: 4.749

10.  9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity.

Authors:  Anne Zuse; Helge Prinz; Klaus Müller; Peter Schmidt; Eckhard G Günther; Frank Schweizer; Jochen H M Prehn; Marek Los
Journal:  Eur J Pharmacol       Date:  2007-08-01       Impact factor: 4.432
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  37 in total

Review 1.  Pituitary stem cell update and potential implications for treating hypopituitarism.

Authors:  Frederic Castinetti; Shannon W Davis; Thierry Brue; Sally A Camper
Journal:  Endocr Rev       Date:  2011-04-14       Impact factor: 19.871

2.  Activation of type II cells into regenerative stem cell antigen-1(+) cells during alveolar repair.

Authors:  Yuru Liu; Varsha Suresh Kumar; Wei Zhang; Jalees Rehman; Asrar B Malik
Journal:  Am J Respir Cell Mol Biol       Date:  2015-07       Impact factor: 6.914

3.  Nestin-expressing cells in the developing, mature and noise-exposed cochlear epithelium.

Authors:  Reiko Watanabe; Maria H Morell; Josef M Miller; Ariane C Kanicki; K Sue O'Shea; Richard A Altschuler; Yehoash Raphael
Journal:  Mol Cell Neurosci       Date:  2011-11-20       Impact factor: 4.314

4.  Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells.

Authors:  Maria Stecklum; Annika Wulf-Goldenberg; Bettina Purfürst; Antje Siegert; Marlen Keil; Klaus Eckert; Iduna Fichtner
Journal:  In Vitro Cell Dev Biol Anim       Date:  2014-10-01       Impact factor: 2.416

Review 5.  Pre-transplantation specification of stem cells to cardiac lineage for regeneration of cardiac tissue.

Authors:  Maritza Mayorga; Amanda Finan; Marc Penn
Journal:  Stem Cell Rev Rep       Date:  2009-01-30       Impact factor: 5.739

6.  Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM alpha) recruits bone marrow-derived cells to the murine pulmonary vasculature.

Authors:  Daniel J Angelini; Qingning Su; Irina A Kolosova; Chunling Fan; John T Skinner; Kazuyo Yamaji-Kegan; Michael Collector; Saul J Sharkis; Roger A Johns
Journal:  PLoS One       Date:  2010-06-22       Impact factor: 3.240

7.  Cytosine methylation dysregulation in neonates following intrauterine growth restriction.

Authors:  Francine Einstein; Reid F Thompson; Tushar D Bhagat; Melissa J Fazzari; Amit Verma; Nir Barzilai; John M Greally
Journal:  PLoS One       Date:  2010-01-26       Impact factor: 3.240

8.  Potential involvement of the stem cell factor receptor c-kit in alopecia areata and androgenetic alopecia: histopathological, immunohistochemical, and semiquantitative investigations.

Authors:  Md Ashrafuzzaman; Tomoko Yamamoto; Noriyuki Shibata; Takeshi Thomas Hirayama; Makio Kobayashi
Journal:  Acta Histochem Cytochem       Date:  2010-02-26       Impact factor: 1.938

9.  Bone marrow-derived stromal cell therapy in cirrhosis: clinical evidence, cellular mechanisms, and implications for the treatment of hepatocellular carcinoma.

Authors:  Jeffrey M Vainshtein; Rafi Kabarriti; Keyur J Mehta; Jayanta Roy-Chowdhury; Chandan Guha
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-07-15       Impact factor: 7.038

10.  Human CD34/CD90 ASCs are capable of growing as sphere clusters, producing high levels of VEGF and forming capillaries.

Authors:  Francesco De Francesco; Virginia Tirino; Vincenzo Desiderio; Giuseppe Ferraro; Francesco D'Andrea; Mariateresa Giuliano; Guido Libondi; Giuseppe Pirozzi; Alfredo De Rosa; Gianpaolo Papaccio
Journal:  PLoS One       Date:  2009-08-06       Impact factor: 3.240
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