Prescribing and monitoring hemodialysis dose.

Small patients require higher Kt/V, the ratio of dialysis dose (the product of small-molecule clearance (K) and dialysis session length (t) to body water volume (V), than large patients. The errors implicit in Kt/V for judging hemodialysis dose are reviewed; methods for prescribing hemodialysis based on new technology are discussed; and thoughts about future development are suggested.