Literature DB >> 18626124

Monitoring adherence and defaulting for antiretroviral therapy in 5 East african countries: an urgent need for standards.

John Chalker1, Tenaw Andualem, Omary Minzi, Joseph Ntaganira, Atieno Ojoo, Paul Waako, Dennis Ross-Degnan.   

Abstract

OBJECTIVES: A cross-sectional survey was performed in 24 systems of care providing antiretroviral medications in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda to examine current practices in monitoring rates of treatment adherence and defaulting.
RESULTS: Only 20 of 48 facilities reported routinely measuring individual patient adherence levels; only 12 measured rates of adherence for the clinic population. The rules for determining which patients were included in the calculation of rates were unclear. Fourteen different definitions of treatment defaulting were in use. Facilities routinely gather potentially useful data, but the frequency of doing so varied widely.
CONCLUSIONS: Individual and program treatment adherence and defaulting are not routinely monitored; when done, the operational definitions and methods varied widely, making comparisons across programs unreliable. There is a pressing need to determine which measures are the most feasible and reliable to collect, the most useful for clinical counseling, and most informative for program management.

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Year:  2008        PMID: 18626124     DOI: 10.1177/1545109708320687

Source DB:  PubMed          Journal:  J Int Assoc Physicians AIDS Care (Chic)        ISSN: 1545-1097


  21 in total

1.  What Time is it? Adherence to Antiretroviral Therapy in Ethiopia.

Authors:  Yordanos M Tiruneh; Ira B Wilson
Journal:  AIDS Behav       Date:  2016-11

2.  Barriers to and facilitators of adherence to pediatric antiretroviral therapy in a sub-Saharan setting: insights from a qualitative study.

Authors:  Bradley C Fetzer; Bavon Mupenda; Jean Lusiama; Faustin Kitetele; Carol Golin; Frieda Behets
Journal:  AIDS Patient Care STDS       Date:  2011-08-08       Impact factor: 5.078

3.  Implementation and operational research: evaluating outcomes of patients lost to follow-up in a large comprehensive care treatment program in western Kenya.

Authors:  Beth Rachlis; Daniel Ochieng; Elvin Geng; Elyne Rotich; Vincent Ochieng; Beryl Maritim; Samson Ndege; Violet Naanyu; Jeffrey N Martin; Alfred Keter; Paul Ayuo; Lameck Diero; Monicah Nyambura; Paula Braitstein
Journal:  J Acquir Immune Defic Syndr       Date:  2015-04-01       Impact factor: 3.731

4.  Measuring adherence to antiretroviral treatment in resource-poor settings: the clinical validity of key indicators.

Authors:  Dennis Ross-Degnan; Marsha Pierre-Jacques; Fang Zhang; Hailu Tadeg; Lillian Gitau; Joseph Ntaganira; Robert Balikuddembe; John Chalker; Anita K Wagner
Journal:  BMC Health Serv Res       Date:  2010-02-19       Impact factor: 2.655

5.  Measuring adherence to antiretroviral treatment in resource-poor settings: the feasibility of collecting routine data for key indicators.

Authors:  John C Chalker; Tenaw Andualem; Lillian N Gitau; Joseph Ntaganira; Celestino Obua; Hailu Tadeg; Paul Waako; Dennis Ross-Degnan
Journal:  BMC Health Serv Res       Date:  2010-02-19       Impact factor: 2.655

6.  Contextual and psychosocial influences on antiretroviral therapy adherence in rural Zimbabwe: towards a systematic framework for programme planners.

Authors:  Morten Skovdal; Catherine Campbell; Kundai Nhongo; Constance Nyamukapa; Simon Gregson
Journal:  Int J Health Plann Manage       Date:  2011-07-10

7.  Clinic Attendance for Medication Refills and Medication Adherence amongst an Antiretroviral Treatment Cohort in Uganda: A Prospective Study.

Authors:  Setor Kunutsor; John Walley; Elly Katabira; Simon Muchuro; Hudson Balidawa; Elizabeth Namagala; Eric Ikoona
Journal:  AIDS Res Treat       Date:  2010-12-19

8.  Multiple ART Programs Create a Dilemma for Providers to Monitor ARV Adherence in Uganda.

Authors:  Celestino Obua; Annelie Gusdal; Paul Waako; John C Chalker; Goran Tomson; Rolf Wahlström; The Inrud-Iaa Team
Journal:  Open AIDS J       Date:  2011-03-18

9.  Adherence to highly active antiretroviral treatment in HIV-infected Rwandan women.

Authors:  Stephenson Musiime; Fred Muhairwe; Alfred Rutagengwa; Eugene Mutimura; Kathryn Anastos; Donald R Hoover; Shi Qiuhu; Elizaphane Munyazesa; Ivan Emile; Annette Uwineza; Ethan Cowan
Journal:  PLoS One       Date:  2011-11-17       Impact factor: 3.240

10.  Using concept mapping to explore why patients become lost to follow up from an antiretroviral therapy program in the Zomba District of Malawi.

Authors:  Beth Rachlis; Farah Ahmad; Monique van Lettow; Adamson S Muula; Medson Semba; Donald C Cole
Journal:  BMC Health Serv Res       Date:  2013-06-11       Impact factor: 2.655

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