Literature DB >> 18624864

Low prescription rate for systemic treatments in the management of severe psoriasis vulgaris and psoriatic arthritis in dermatological practices in Berlin and Brandenburg, Germany: results from a patient registry.

A Nast1, N Reytan, S Rosumeck, R Erdmann, B Rzany.   

Abstract

BACKGROUND: Many treatment options are available for the management of psoriasis vulgaris. However, detailed data on prescription behaviour in Germany, especially with regard to the use of new treatment options (e.g. biologics) in private practices, are lacking.
OBJECTIVE: To assess the treatment choices being made in the management of psoriasis vulgaris and psoriatic arthritis in private dermatological practices.
METHODS: We established a patient registry that documented the treatment decisions taken during 4797 patient visits between January 2006 and September 2006 with regard to disease activity and concomitant psoriatic arthritis.
RESULTS: Corticosteroids were the most frequently prescribed topical treatment, and methotrexate and fumaric acid esters were the most frequently prescribed systemic treatments. Biologics were prescribed in only 2% of patient visits. Systemic treatments were prescribed in only 31% of visits made by patients suffering from moderate to severe psoriasis (which was diagnosed in 48% of all patient visits) and in only 58% of visits made by patients suffering from psoriatic arthritis (which was diagnosed in 12% of all patient visits).
CONCLUSIONS: Anti-psoriatic treatment was too often limited to topical agents. The rather small percentage of patients with moderate to severe psoriasis or psoriatic arthritis who received systemic therapy indicates that the use of systemic treatments in our sample was too restrictive. Novel therapeutic options such as biologics were rarely used in private practices. New strategies to improve the quality of care provided to patients suffering from severe psoriasis are needed.

Entities:  

Mesh:

Year:  2008        PMID: 18624864     DOI: 10.1111/j.1468-3083.2008.02841.x

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  7 in total

1.  [Current status of oral immunomodulatory and immunosuppressive agents].

Authors:  S Meller; A M Baran; S A Braun; N Klossowski; B Homey
Journal:  Hautarzt       Date:  2014-02       Impact factor: 0.751

2.  Methotrexate use and liver disease--a causal relationship?

Authors:  J Schmitt; J A Singh
Journal:  Br J Dermatol       Date:  2014-07       Impact factor: 9.302

3.  Contemporary treatment patterns in plaque psoriasis and psoriatic arthritis.

Authors:  Dorota Jenerowicz; Justyna Kaznowska; Paweł Bartkiewicz; Anna Sadowska-Przytocka; Marcin Szymkowiak; Zygmunt Adamski; Magdalena Czarnecka-Operacz
Journal:  Postepy Dermatol Alergol       Date:  2020-04-09       Impact factor: 1.837

Review 4.  Large-scale, prospective, observational studies in patients with psoriasis and psoriatic arthritis: A systematic and critical review.

Authors:  Sue Langham; Julia Langham; Hans-Peter Goertz; Mark Ratcliffe
Journal:  BMC Med Res Methodol       Date:  2011-03-31       Impact factor: 4.615

Review 5.  The possibilities and principles of methotrexate treatment of psoriasis - the updated knowledge.

Authors:  Magdalena Czarnecka-Operacz; Anna Sadowska-Przytocka
Journal:  Postepy Dermatol Alergol       Date:  2014-12-03       Impact factor: 1.837

6.  Physician perspectives in the management of psoriasis and psoriatic arthritis: results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis survey.

Authors:  P C M van de Kerkhof; K Reich; A Kavanaugh; H Bachelez; J Barker; G Girolomoni; R G Langley; C F Paul; L Puig; M G Lebwohl
Journal:  J Eur Acad Dermatol Venereol       Date:  2015-04-16       Impact factor: 6.166

7.  Therapeutic goals and treatment response evaluation in moderate to severe psoriasis: an experts opinion document.

Authors:  Isabel Belinchón Romero; Esteban Dauden; Carlos Ferrándiz Foraster; Álvaro González-Cantero; Jose Manuel Carrascosa Carrillo
Journal:  Ann Med       Date:  2021-12       Impact factor: 4.709

  7 in total

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