Literature DB >> 18623587

A versatile oxygenator and perfusion system for magnetic resonance studies.

M P Gamcsik1, J R Forder, K K Millis, K A McGovern.   

Abstract

A compact, reusable membrane oxygenator has been constructed for the perfusion of cultured cells and isolated organs. While the oxygenator was designed to be compatible with nuclear magnetic resonance (NMR) spectroscopy studies, it can also be used for any experiment which requires warming and oxygenation of perfusates. For the NMR studies, the oxygenator can be positioned at the opening of the magnet bore which allows oxygenation and warming of the perfusate immediately prior to delivery to the tissue, therefore eliminating problems with heat or oxygen loss which may occur with the long perfusion lines. (c) 1996 John Wiley & Sons, Inc.

Entities:  

Year:  1996        PMID: 18623587     DOI: 10.1002/bit.260490302

Source DB:  PubMed          Journal:  Biotechnol Bioeng        ISSN: 0006-3592            Impact factor:   4.530


  7 in total

1.  Simultaneous noninvasive determination of regional myocardial perfusion and oxygen content in rabbits: toward direct measurement of myocardial oxygen consumption at MR imaging.

Authors:  S B Reeder; A A Holmes; E R McVeigh; J R Forder
Journal:  Radiology       Date:  1999-09       Impact factor: 11.105

2.  Metabolic phenotyping of the diseased rat heart using 13C-substrates and ex vivo perfusion in the working mode.

Authors:  Geneviève Vincent; Maya Khairallah; Bertrand Bouchard; Christine Des Rosiers
Journal:  Mol Cell Biochem       Date:  2003-01       Impact factor: 3.396

Review 3.  New advances in MR-compatible bioartificial liver.

Authors:  Rex E Jeffries; Jeffrey M Macdonald
Journal:  NMR Biomed       Date:  2011-02-20       Impact factor: 4.044

4.  Hyperpolarized (13)C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism.

Authors:  Kayvan R Keshari; John Kurhanewicz; Rex E Jeffries; David M Wilson; Brian J Dewar; Mark Van Criekinge; Matthew Zierhut; Daniel B Vigneron; Jeffrey M Macdonald
Journal:  Magn Reson Med       Date:  2010-02       Impact factor: 4.668

5.  Effect of oxygen concentration on viability and metabolism in a fluidized-bed bioartificial liver using ³¹P and ¹³C NMR spectroscopy.

Authors:  Rex E Jeffries; Michael P Gamcsik; Kayvan R Keshari; Peter Pediaditakis; Andrey P Tikunov; Gregory B Young; Haakil Lee; Paul B Watkins; Jeffrey M Macdonald
Journal:  Tissue Eng Part C Methods       Date:  2012-09-28       Impact factor: 3.056

6.  Direct Detection of Glutathione Biosynthesis, Conjugation, Depletion and Recovery in Intact Hepatoma Cells.

Authors:  Rex E Jeffries; Shawn M Gomez; Jeffrey M Macdonald; Michael P Gamcsik
Journal:  Int J Mol Sci       Date:  2022-04-25       Impact factor: 5.923

7.  A Microperfusion and In-Bore Oxygenator System Designed for Magnetic Resonance Microscopy Studies on Living Tissue Explants.

Authors:  Jeremy J Flint; Kannan Menon; Brian Hansen; John Forder; Stephen J Blackband
Journal:  Sci Rep       Date:  2015-12-15       Impact factor: 4.379

  7 in total

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