Literature DB >> 18622906

Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.

Yi Liu1, Zulfiqar Ali, Ikhlas A Khan.   

Abstract

Phytochemical investigation of the fruits of Momordica charantia resulted in the isolation and characterization of two new (1 and 2) and eight known cucurbitane-type triterpene glycosides and one cucurbitane-type triterpene. The glycosides (7beta,25-dimethoxycucurbita-5(6),23( E)-dien-19-al 3- O-beta-D-allopyranoside (1); 25-methoxycucurbita-5(6),23(E)-dien-19-ol 3-O-beta-D-allopyranoside (2); momordicosides A, F (1), F (2), G, K, and L; and goyaglycoside-c and goyaglycoside-d) and the triterpene [3 beta,7 beta,25-trihydroxycucurbita-5,23(E)-dien-19-al] were characterized by physical, chemical, and spectroscopic techniques, including 1D- and 2D-NMR as well as by comparison with the reported data.

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Year:  2008        PMID： 18622906     DOI： 10.1055/s-2008-1081297

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  6 in total

1.  Inhibition of nuclear transcription factor-κB and activation of peroxisome proliferator-activated receptors in HepG2 cells by cucurbitane-type triterpene glycosides from Momordica charantia.

Authors:  Nguyen Xuan Nhiem; Pham Hai Yen; Nguyen Thi Thanh Ngan; Tran Hong Quang; Phan Van Kiem; Chau Van Minh; Bui Huu Tai; Nguyen Xuan Cuong; Seok Bean Song; Young Ho Kim
Journal:  J Med Food       Date:  2012-01-16       Impact factor: 2.786

2.  13, 14-Epoxyoleanan-3-ol-acetate: A Male Fertility-Enhancing Constituent from Hexane Fraction of Momordica charantia L. (Cucurbitaceae).

Authors:  Oluwasegun Adedokun; Adebayo Gbolade; Bunyaminu Ayinde
Journal:  Turk J Pharm Sci       Date:  2022-04-29

Review 3.  Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy.

Authors:  Komal Raina; Dileep Kumar; Rajesh Agarwal
Journal:  Semin Cancer Biol       Date:  2016-07-21       Impact factor: 15.707

Review 4.  Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome.

Authors:  Md Ashraful Alam; Riaz Uddin; Nusrat Subhan; Md Mahbubur Rahman; Preeti Jain; Hasan Mahmud Reza
Journal:  J Lipids       Date:  2015-01-12

5.  De novo transcriptome analysis and identification of candidate genes associated with triterpenoid biosynthesis in Trichosanthes cucumerina L.

Authors:  Pornpatsorn Lertphadungkit; Xue Qiao; Supaart Sirikantaramas; Veena Satitpatipan; Min Ye; Somnuk Bunsupa
Journal:  Plant Cell Rep       Date:  2021-07-06       Impact factor: 4.570

6.  Cucurbitane-Type Triterpene Glycosides from Momordica charantia and Their α-Glucosidase Inhibitory Activities.

Authors:  Ya Gao; Jian-Chao Chen; Xing-Rong Peng; Zhong-Rong Li; Hai-Guo Su; Ming-Hua Qiu
Journal:  Nat Prod Bioprospect       Date:  2020-05-06
  6 in total

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