Ashok Gupta1, Aleksander M Vitali, Ralph Rothstein, D Douglas Cochrane. 1. Division of Pediatric Neurosurgery, Department of Pediatric Surgery, British Columbia Children's Hospital/Children's and Women's Health Centre, 4480 Oak St, #K3-159, Vancouver, BC, Canada.
Abstract
INTRODUCTION: The association between hypopituitarism, Chiari I malformation, and syringomyelia has been recently recognized. Most of the reported patients suffered perinatal injury or asphyxia. MATERIALS AND METHODS: We present the case of a premature child without identifiable perinatal injury, who was recognized to have growth hormone (GH) deficiency, Chiari I malformation, and syringohydromyelia. CONCLUSION: There was a resolution of syrinx and tonsillar herniation after GH replacement.
INTRODUCTION: The association between hypopituitarism, Chiari I malformation, and syringomyelia has been recently recognized. Most of the reported patients suffered perinatal injury or asphyxia. MATERIALS AND METHODS: We present the case of a premature child without identifiable perinatal injury, who was recognized to have growth hormone (GH) deficiency, Chiari I malformation, and syringohydromyelia. CONCLUSION: There was a resolution of syrinx and tonsillar herniation after GH replacement.
Authors: R Shane Tubbs; John C Wellons; Matthew D Smyth; Alfred A Bartolucci; Jeffrey P Blount; W Jerry Oakes; Paul A Grabb Journal: Pediatr Neurosurg Date: 2003-06 Impact factor: 1.162
Authors: Christina A Markunas; Karen Soldano; Kaitlyn Dunlap; Heidi Cope; Edgar Asiimwe; Jeffrey Stajich; David Enterline; Gerald Grant; Herbert Fuchs; Simon G Gregory; Allison E Ashley-Koch Journal: PLoS One Date: 2013-04-19 Impact factor: 3.240