Literature DB >> 18622432

Reversible siRNA-polymer conjugates by RAFT polymerization.

Karina L Heredia1, Thi H Nguyen, Chien-Wen Chang, Volga Bulmus, Thomas P Davis, Heather D Maynard.   

Abstract

A straightforward synthetic method to prepare pyridyl disulfide end functionalized poly(PEG acrylate) by RAFT polymerization for efficient and reversible conjugation to siRNA is described.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18622432     DOI： 10.1039/b804812f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  20 in total

1.  Synthesis of folate-functionalized RAFT polymers for targeted siRNA delivery.

Authors:  Danielle S W Benoit; Selvi Srinivasan; Andrew D Shubin; Patrick S Stayton
Journal:  Biomacromolecules       Date:  2011-06-10       Impact factor: 6.988

2.  Heterotelechelic Polymers for Capture and Release of Protein-Polymer Conjugates.

Authors:  Karina L Heredia; Lei Tao; Gregory N Grover; Heather D Maynard
Journal:  J Polym Sci A Polym Chem       Date:  2010-04-01       Impact factor: 2.702

Review 3.  Protein-polymer conjugates: synthetic approaches by controlled radical polymerizations and interesting applications.

Authors:  Gregory N Grover; Heather D Maynard
Journal:  Curr Opin Chem Biol       Date:  2010-11-10       Impact factor: 8.822

4.  Degradable PEGylated Protein Conjugates Utilizing RAFT Polymerization.

Authors:  Caitlin G Decker; Heather D Maynard
Journal:  Eur Polym J       Date:  2015-04-01       Impact factor: 4.598

5.  Emerging synthetic approaches for protein-polymer conjugations.

Authors:  Rebecca M Broyer; Gregory N Grover; Heather D Maynard
Journal:  Chem Commun (Camb)       Date:  2011-01-12       Impact factor: 6.222

Review 6.  Degradable vinyl polymers for biomedical applications.

Authors:  Vianney Delplace; Julien Nicolas
Journal:  Nat Chem       Date:  2015-10       Impact factor: 24.427

7.  Facile synthesis of multivalent folate-block copolymer conjugates via aqueous RAFT polymerization: targeted delivery of siRNA and subsequent gene suppression.

Authors:  Adam W York; Yilin Zhang; Andrew C Holley; Yanlin Guo; Faqing Huang; Charles L McCormick
Journal:  Biomacromolecules       Date:  2009-04-13       Impact factor: 6.988

8.  Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.

Authors:  Craig L Duvall; Anthony J Convertine; Danielle S W Benoit; Allan S Hoffman; Patrick S Stayton
Journal:  Mol Pharm       Date:  2010-04-05       Impact factor: 4.939

9.  Synthesis of a pyridyl disulfide end-functionalized glycopolymer for conjugation to biomolecules and patterning on gold surfaces.

Authors:  Vimary Vázquez-Dorbatt; Zachary P Tolstyka; Chien-Wen Chang; Heather D Maynard
Journal:  Biomacromolecules       Date:  2009-08-10       Impact factor: 6.988

10.  Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers.

Authors:  Adam W York; Faqing Huang; Charles L McCormick
Journal:  Biomacromolecules       Date:  2010-02-08       Impact factor: 6.988
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.