Literature DB >> 18622380

[Prognostic factors for survival in primary liver cancer].

T Frangov, R Gaĭdarski, V Dimitrova, V Popov, K Grozeva, D Rusenov.   

Abstract

BACKGROUND: The aim of this study was to identify the prognostic factors of survival after curative resection of primary liver cancer (PLC). STUDY
DESIGN: Thirty four patients underwent resection PLC between January 1991 and December 2000. Univariate and multivariable analysis were used to retrospectively identify factors associated with overall survival when resection was curative for primary tumor.
RESULTS: Overall 1, 2, 3 and 5 - year survival rates were 76.0%, 57.5%, 35.2% and 6.0% respectively. Recurrence after one year was 35%. Eleven predictive factors - clinical, laboratory, pathological and surgical were analyzed. Independent prognostic factors for overall survival were vascular invasion (p = 0.006) and stage (p = 0.023).
CONCLUSIONS: Hepatic resection is an effective treatment for PLC, even in advanced cases. The overall survival were low, because of late diagnosis and recurrence of the tumors.

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Mesh:

Year:  2007        PMID: 18622380

Source DB:  PubMed          Journal:  Khirurgiia (Sofiia)        ISSN: 0450-2167


  3 in total

1.  SPHK1 inhibitor suppresses cell proliferation and invasion associated with the inhibition of NF-κB pathway in hepatocellular carcinoma.

Authors:  Zijie Zhang; Zhenyu Yan; Zheng Yuan; Yanzhen Sun; Haifa He; Chunyang Mai
Journal:  Tumour Biol       Date:  2014-12-24

2.  Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy.

Authors:  Wei Cheng; Aimudula Ainiwaer; Lei Xiao; Qian Cao; Ge Wu; Ying Yang; Rui Mao; Yongxing Bao
Journal:  Mol Med Rep       Date:  2015-05-04       Impact factor: 2.952

3.  The effect of chemokine CC motif ligand 19 on the proliferation and migration of hepatocellular carcinoma.

Authors:  Ke-Qin Luo; Yi-Ni Shi; Ji-Cai Peng
Journal:  Tumour Biol       Date:  2014-09-16
  3 in total

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