Literature DB >> 18621990

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network.

Eric Dessaud1, Andrew P McMahon, James Briscoe.   

Abstract

Neuronal subtype specification in the vertebrate neural tube is one of the best-studied examples of embryonic pattern formation. Distinct neuronal subtypes are generated in a precise spatial order from progenitor cells according to their location along the anterior-posterior and dorsal-ventral axes. Underpinning this organization is a complex network of multiple extrinsic and intrinsic factors. This review focuses on the molecular mechanisms and general strategies at play in ventral regions of the forming spinal cord, where sonic hedgehog-based morphogen signaling is a key determinant. We discuss recent advances in our understanding of these events and highlight unresolved questions.

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Year:  2008        PMID: 18621990     DOI: 10.1242/dev.009324

Source DB:  PubMed          Journal:  Development        ISSN: 0950-1991            Impact factor:   6.868


  310 in total

1.  Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.

Authors:  Floor J Stam; Timothy J Hendricks; Jingming Zhang; Eric J Geiman; Cedric Francius; Patricia A Labosky; Frederic Clotman; Martyn Goulding
Journal:  Development       Date:  2011-11-24       Impact factor: 6.868

Review 2.  Shaping sound in space: the regulation of inner ear patterning.

Authors:  Andrew K Groves; Donna M Fekete
Journal:  Development       Date:  2012-01       Impact factor: 6.868

3.  A computational statistics approach for estimating the spatial range of morphogen gradients.

Authors:  Jitendra S Kanodia; Yoosik Kim; Raju Tomer; Zia Khan; Kwanghun Chung; John D Storey; Hang Lu; Philipp J Keller; Stanislav Y Shvartsman
Journal:  Development       Date:  2011-10-17       Impact factor: 6.868

Review 4.  REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.

Authors:  Irfan A Qureshi; Solen Gokhan; Mark F Mehler
Journal:  Cell Cycle       Date:  2010-11-15       Impact factor: 4.534

5.  Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development.

Authors:  Alexander S Brown; Douglas J Epstein
Journal:  Development       Date:  2011-08-10       Impact factor: 6.868

6.  Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus.

Authors:  Aurore Thélie; Simon Desiderio; Julie Hanotel; Ian Quigley; Benoit Van Driessche; Anthony Rodari; Mark D Borromeo; Sadia Kricha; François Lahaye; Jenifer Croce; Gustavo Cerda-Moya; Jesús Ordoño Fernandez; Barbara Bolle; Katharine E Lewis; Maike Sander; Alessandra Pierani; Michael Schubert; Jane E Johnson; Christopher R Kintner; Tomas Pieler; Carine Van Lint; Kristine A Henningfeld; Eric J Bellefroid; Claude Van Campenhout
Journal:  Development       Date:  2015-10-01       Impact factor: 6.868

7.  Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons.

Authors:  Lei Zhang; Jiu-Chao Yin; Hana Yeh; Ning-Xin Ma; Grace Lee; Xiangyun Amy Chen; Yanming Wang; Li Lin; Li Chen; Peng Jin; Gang-Yi Wu; Gong Chen
Journal:  Cell Stem Cell       Date:  2015-10-17       Impact factor: 24.633

8.  Neogenin regulates Sonic Hedgehog pathway activity during digit patterning.

Authors:  Mingi Hong; Karen A Schachter; Guoying Jiang; Robert S Krauss
Journal:  Dev Dyn       Date:  2012-03       Impact factor: 3.780

9.  Modeling of human neurulation using bioengineered pluripotent stem cell culture.

Authors:  Xufeng Xue; Ryan P Wang; Jianping Fu
Journal:  Curr Opin Biomed Eng       Date:  2020-02-17

10.  Axon-glial interactions at the Drosophila CNS midline.

Authors:  Stephen T Crews
Journal:  Cell Adh Migr       Date:  2010-01-29       Impact factor: 3.405

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