Literature DB >> 18621498

A real-time polymerase chain reaction for the detection of Streptococcus pneumoniae in blood using a mouse model: a potential new "gold standard".

Nadine G Rouphael1, Nikkol Atwell-Melnick, Dana Longo, Melissa Whaley, George M Carlone, Jackie S Sampson, Edwin W Ades.   

Abstract

Better diagnostics for pneumococcal disease are urgently needed. In a murine model, real-time polymerase chain reaction was superior to conventional culture in detecting pneumococcus in blood, particularly in early disease and after antibiotic administration, and could distinguish between commensalism and infection.

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Year:  2008        PMID： 18621498     DOI： 10.1016/j.diagmicrobio.2008.06.002

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  3 in total

1.  Diagnostic value of serum pneumococcal DNA load during invasive pneumococcal infections.

Authors:  A J H Cremers; F Hagen; P W M Hermans; J F Meis; G Ferwerda
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-01-22       Impact factor: 3.267

2.  Prevalence, Risk Factors, and Outcomes of Bacteremic Pneumonia in Children.

Authors:  Cristin Q Fritz; Kathryn M Edwards; Wesley H Self; Carlos G Grijalva; Yuwei Zhu; Sandra R Arnold; Jonathan A McCullers; Krow Ampofo; Andrew T Pavia; Richard G Wunderink; Evan J Anderson; Anna M Bramley; Seema Jain; Derek J Williams
Journal:  Pediatrics       Date:  2019-07       Impact factor: 7.124

3.  Evaluation of chest radiography, lytA real-time PCR, and other routine tests for diagnosis of community-acquired pneumonia and estimation of possible attributable fraction of pneumococcus in northern Togo.

Authors:  A Blake; B M Njanpop-Lafourcade; J N Telles; A Rajoharison; M S Makawa; K Agbenoko; S Tamekloe; J E Mueller; H Tall; B D Gessner; G Paranhos-Baccalà; J C Moïsi
Journal:  Epidemiol Infect       Date:  2016-11-17       Impact factor: 2.451
  3 in total

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