Literature DB >> 18620551

Applying logic to pulmonary artery catheter use.

Horst E Kunig, Michael R Pinsky, Lothar Engelmann.   

Abstract

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Year:  2008        PMID: 18620551      PMCID: PMC2575551          DOI: 10.1186/cc6928

Source DB:  PubMed          Journal:  Crit Care        ISSN: 1364-8535            Impact factor:   9.097


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Mansour and colleagues recommend not routinely using the pulmonary artery catheter to guide hemodynamic management in the intensive care unit, because the perceived benefits are largely intangible [1]. Pulmonary artery catheter monitoring of the right ventricular ejection fraction (RVef) and of the right ventricular end-diastolic volume (EDV), however, reflects powerful yet underutilized relationships that assess right ventricular performance. Since the cardiac output equals the product of the RVef, the EDV and the heart rate, one can assess the RVef to EDV relations as direct measures of right ventricular performance. A series of RVef, EDV and heart rate combinations can give the same cardiac output (Figure 1); monitoring or targeting cardiac output alone ignores this reality. For example, in hypovolemia the EDV is low and the RVef is increased, whereas in right ventricular failure the opposite is true. Furthermore, resuscitation from hypovolemia will increase the EDV and decrease the RVef [2], while reversal of cor pulmonale will decrease the EDV and increase the RVef.
Figure 1

Right ventricular ejection fraction, right ventricular end-diastolic volume and heart rate relationship with cardiac output. CO, cardiac output; EDV, right ventricular end-diastolic volume; HR, heart rate; RVef, right ventricular ejection fraction.

Right ventricular ejection fraction, right ventricular end-diastolic volume and heart rate relationship with cardiac output. CO, cardiac output; EDV, right ventricular end-diastolic volume; HR, heart rate; RVef, right ventricular ejection fraction. No monitoring device other than the pulmonary artery catheter can continually assess these variables. These concepts are often used in the cardiac surgery suite, but are rarely codified for diagnosis and management. Monitoring devices can improve outcome only if they are coupled to treatments that improve outcome. Applying the above logic to previously proposed treatment protocols, such as using the mixed venous oxygen saturation [3], may therefore be the first step toward defining pulmonary artery catheter utility [4].

Abbreviations

EDV = right ventricular end-diastolic volume; RVef = right ventricular ejection fraction.

Competing interests

The authors declare that they have no competing interests.
  4 in total

Review 1.  The pulmonary artery catheter: in medio virtus.

Authors:  Jean-Louis Vincent; Michael R Pinsky; Charles L Sprung; Mitchell Levy; John J Marini; Didier Payen; Andrew Rhodes; Jukka Takala
Journal:  Crit Care Med       Date:  2008-11       Impact factor: 7.598

2.  Right ventricular function in human sepsis: a thermodilution study.

Authors:  J F Dhainaut; M R Pinsky; S Nouria; F Slomka; F Brunet
Journal:  Chest       Date:  1997-10       Impact factor: 9.410

3.  Let us use the pulmonary artery catheter correctly and only when we need it.

Authors:  Michael R Pinsky; Jean-Louis Vincent
Journal:  Crit Care Med       Date:  2005-05       Impact factor: 7.598

4.  PAC in FACTT: time to PAC it in?

Authors:  Wissam Mansour; Eric B Milbrandt; Lillian L Emlet
Journal:  Crit Care       Date:  2008-02-06       Impact factor: 9.097

  4 in total

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