Literature DB >> 18620414

Total synthesis of (+/-)-2-O-methylneovibsanin H.

Annette P-J Chen1, Craig M Williams.   

Abstract

The total synthesis of (+/-)-2- O-methylneovibsanin H was achieved in 12 steps. An acid-catalyzed, one-pot, four-step cascade reaction was key to the concise total synthesis, lending support to the proposed biosynthesis.

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Year:  2008        PMID： 18620414     DOI： 10.1021/ol801117e

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Towards the Total Synthesis of 3-Hydroxyvibsanin E.

Authors:  Brett D Schwartz; Justin R Denton; Paul V Bernhardt; Huw M L Davies; Craig M Williams
Journal:  Synthesis (Stuttg)       Date:  2009-09-01       Impact factor: 3.157

Review 2.  Neurotrophic natural products: chemistry and biology.

Authors:  Jing Xu; Michelle H Lacoske; Emmanuel A Theodorakis
Journal:  Angew Chem Int Ed Engl       Date:  2013-12-18       Impact factor: 15.336

3.  Neovibsanin B inhibits human malignant brain tumor cell line proliferation and induces apoptosis.

Authors:  Yi-Fen Cui; Xiao-Lin Yuan; Wen-Hai Fan; Sheng-Fan Li; Yu-Qin Deng; Qing Zhang; Chun-Lei Zhang; Zhen Yang
Journal:  Int J Clin Exp Med       Date:  2015-04-15

4.  Total Synthesis of (±)-Vibsanin E.

Authors:  Brett D Schwartz; Justin R Denton; Huw M L Davies; Craig M Williams
Journal:  Aust J Chem       Date:  2009       Impact factor: 1.321

5.  Protective effect of neovibsanin B on spatial cognitive functions of rats with cerebrovascular hypoperfusion.

Authors:  Xing-Wang Chen; Yong-Tao Lv; Ye Han; Ying Huan; Xiao-Ya Feng; Chun-Fu Chen
Journal:  Int J Clin Exp Med       Date:  2015-08-15
  5 in total

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