Literature DB >> 18619277

[Studies on the antioxidative activity of polysaccharides from radix Saposhnikoviae].

Ze-Qing Zhang1, Ying-Juan Tian, Jing Zhang.   

Abstract

OBJECTIVE: To research the antioxidant activity of polysaccharides from Saposhnikovia divaricata (Turez.) Schischk.
METHOD: Polysaccharides from Saposhnikovia divaricata (Turez.) Schischk were obtained through hot water extracting and ethanol precipitating method. Using CTAB as precipitant, Saposhnikovia polysaccharide was separated into acid Saposhnikovia polysaccharide (A-SPS) and neutral Saposhnikovia polysaccharide (N-SPS). The total reducing power, scavenging effect to superoixide anion (O2-*), hydroxyl radical (*OH), 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH*) and inhibiting effect to lipid-peroxidation induced by Fe2+ of different Saposhnikovia polysaccharides were measured in vitro chemical simulated systems for evaluating their antioxidant activity.
RESULTS: Saposhnikovia polysaccharides had some functions of scavenging free radicals and inhibiting lipid peroxidation, and scavenging effects on DPPH* and OH* were especially significant. A-SPS had better effect among different Saposhnikovia polysaccharides, and the scavenging rate of DPPH* and OH* could approach to 70% when the experimental concentration was 8 mg/ml .
CONCLUSION: A-SPS, potential main active ingredient of Saposhnikovia polysaccharide, has strong antioxidant activity and can be applied as a potential natural antioxidant in food and medicine industry.

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Year:  2008        PMID: 18619277

Source DB:  PubMed          Journal:  Zhong Yao Cai        ISSN: 1001-4454


  7 in total

1.  Chinese Medicine Formula "Jian-Pi-Zhi-Dong Decoction" Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice.

Authors:  Dao-Han Wang; Wei Li; Xiao-Fang Liu; Jin-Ming Zhang; Su-Mei Wang
Journal:  Evid Based Complement Alternat Med       Date:  2013-02-03       Impact factor: 2.629

2.  The Modified JiuWei QiangHuo Decoction Alleviated Severe Lung Injury Induced by H1N1 Influenza Virus by Regulating the NF- κ B Pathway in Mice.

Authors:  Lijuan Chen; Xin Yan; Qianlin Yan; Jiajun Fan; Hai Huang; Xunlong Shi; Lei Han; Tianxiong Han; Haiyan Zhu
Journal:  Evid Based Complement Alternat Med       Date:  2015-05-18       Impact factor: 2.629

3.  Polysaccharide enhances Radix Saposhnikoviae efficacy through inhibiting chromones decomposition in intestinal tract.

Authors:  Jing-Ming Yang; Hua Jiang; Hong-Liang Dai; Zi-Wei Wang; Gui-Zhi Jia; Xiang-Cai Meng
Journal:  Sci Rep       Date:  2016-09-06       Impact factor: 4.379

4.  Feeble Antipyretic, Analgesic, and Anti-inflammatory Activities were Found with Regular Dose 4'-O-β-D-Glucosyl-5-O-Methylvisamminol, One of the Conventional Marker Compounds for Quality Evaluation of Radix Saposhnikoviae.

Authors:  Jing-Ming Yang; Hua Jiang; Hong-Liang Dai; Zi-Wei Wang; Gui-Zhi Jia; Xiang-Cai Meng
Journal:  Pharmacogn Mag       Date:  2017 Jan-Mar       Impact factor: 1.085

5.  Simultaneous Determination of Six Chromones in Saposhnikoviae Radix via Quantitative Analysis of Multicomponents by Single Marker.

Authors:  Jinhua Zhang; Luxiao Chen; Junna Qiu; Yu Zhang; Lu Wang; Lijuan Jiang; Yanyan Jiang; Bin Liu
Journal:  J Anal Methods Chem       Date:  2020-04-14       Impact factor: 2.193

Review 6.  Saposhnikovia divaricata-An Ethnopharmacological, Phytochemical and Pharmacological Review.

Authors:  Min Yang; Cong-Cong Wang; Wen-le Wang; Jian-Ping Xu; Jie Wang; Chun-Hong Zhang; Min-Hui Li
Journal:  Chin J Integr Med       Date:  2020-04-21       Impact factor: 1.978

7.  Effect of Juice and Extracts from Saposhnikovia divaricata Root on the Colon Cancer Cells Caco-2.

Authors:  Magdalena Matusiewicz; Katarzyna Barbara Bączek; Iwona Kosieradzka; Tomasz Niemiec; Marta Grodzik; Jarosław Szczepaniak; Sylwia Orlińska; Zenon Węglarz
Journal:  Int J Mol Sci       Date:  2019-09-12       Impact factor: 5.923

  7 in total

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