Literature DB >> 18616967

The Genome Sequencer FLX System--longer reads, more applications, straight forward bioinformatics and more complete data sets.

Marcus Droege1, Brendon Hill.   

Abstract

The Genome Sequencer FLX System (GS FLX), powered by 454 Sequencing, is a next-generation DNA sequencing technology featuring a unique mix of long reads, exceptional accuracy, and ultra-high throughput. It has been proven to be the most versatile of all currently available next-generation sequencing technologies, supporting many high-profile studies in over seven applications categories. GS FLX users have pursued innovative research in de novo sequencing, re-sequencing of whole genomes and target DNA regions, metagenomics, and RNA analysis. 454 Sequencing is a powerful tool for human genetics research, having recently re-sequenced the genome of an individual human, currently re-sequencing the complete human exome and targeted genomic regions using the NimbleGen sequence capture process, and detected low-frequency somatic mutations linked to cancer.

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Year:  2008        PMID: 18616967     DOI: 10.1016/j.jbiotec.2008.03.021

Source DB:  PubMed          Journal:  J Biotechnol        ISSN: 0168-1656            Impact factor:   3.307


  79 in total

1.  Distinct ectomycorrhizospheres share similar bacterial communities as revealed by pyrosequencing-based analysis of 16S rRNA genes.

Authors:  S Uroz; P Oger; E Morin; P Frey-Klett
Journal:  Appl Environ Microbiol       Date:  2012-02-03       Impact factor: 4.792

2.  Characterization and expression analysis of the myeloid differentiation factor 88 (MyD88) in rock bream Oplegnathus fasciatus.

Authors:  Ilson Whang; Youngdeuk Lee; Hyowon Kim; Sung-Ju Jung; Myung-Joo Oh; Cheol Young Choi; Woo Song Lee; Se-Jae Kim; Jehee Lee
Journal:  Mol Biol Rep       Date:  2010-12-09       Impact factor: 2.316

3.  Soil Parameters Drive the Structure, Diversity and Metabolic Potentials of the Bacterial Communities Across Temperate Beech Forest Soil Sequences.

Authors:  M Jeanbille; M Buée; C Bach; A Cébron; P Frey-Klett; M P Turpault; S Uroz
Journal:  Microb Ecol       Date:  2015-09-14       Impact factor: 4.552

4.  Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase.

Authors:  Shane R Wesener; Vishwakanth Y Potharla; Yi-Qiang Cheng
Journal:  Appl Environ Microbiol       Date:  2010-12-23       Impact factor: 4.792

5.  Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences.

Authors:  Tanzy M T Love; Sally W Thurston; Michael C Keefer; Stephen Dewhurst; Ha Youn Lee
Journal:  J Virol       Date:  2010-03-24       Impact factor: 5.103

6.  Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patients.

Authors:  Luke C Swenson; Theresa Mo; Winnie W Y Dong; Xiaoyin Zhong; Conan K Woods; Mark A Jensen; Alexander Thielen; Douglass Chapman; Marilyn Lewis; Ian James; Jayvant Heera; Hernan Valdez; P Richard Harrigan
Journal:  J Infect Dis       Date:  2011-01-15       Impact factor: 5.226

7.  Two-stage design of sequencing studies for testing association with rare variants.

Authors:  Fan Yang; Duncan C Thomas
Journal:  Hum Hered       Date:  2011-07-02       Impact factor: 0.444

8.  Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing.

Authors:  Weihong Qi; Michael Käser; Katharina Röltgen; Dorothy Yeboah-Manu; Gerd Pluschke
Journal:  PLoS Pathog       Date:  2009-09-11       Impact factor: 6.823

9.  Draft genome sequencing of giardia intestinalis assemblage B isolate GS: is human giardiasis caused by two different species?

Authors:  Oscar Franzén; Jon Jerlström-Hultqvist; Elsie Castro; Ellen Sherwood; Johan Ankarklev; David S Reiner; Daniel Palm; Jan O Andersson; Björn Andersson; Staffan G Svärd
Journal:  PLoS Pathog       Date:  2009-08-21       Impact factor: 6.823

10.  Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine.

Authors:  Marcus J Claesson; Orla O'Sullivan; Qiong Wang; Janne Nikkilä; Julian R Marchesi; Hauke Smidt; Willem M de Vos; R Paul Ross; Paul W O'Toole
Journal:  PLoS One       Date:  2009-08-20       Impact factor: 3.240

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