Literature DB >> 18615939

Understanding HIV viral load: implications for counselling.

Patrick O'Byrne1, Paul A MacPherson.   

Abstract

This paper provides an overview of HIV viral loads in blood and genital fluids and how these relate to HIV transmission during sexual activity. Current knowledge around HIV viral loads and transmission are then discussed in relation to HIV disclosure laws in Canada. HIV counsellors and health care workers should ensure that their clients/patients are aware that blood viral load is not necessarily equivalent to genital tract viral load and that the development of drug resistance within the two compartments may be unrelated. This is an important factor in preventing the spread of HIV as well as for HIV-positive individuals in not unintentionally exposing themselves to potential legal repercussions.

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Year:  2008        PMID: 18615939      PMCID: PMC6976165     

Source DB:  PubMed          Journal:  Can J Public Health        ISSN: 0008-4263


  26 in total

1.  Limited penetration of lopinavir into seminal plasma of HIV-1-infected men.

Authors:  Sanjay U C Sankatsing; Jackie Droste; David Burger; Rieneke M E Van Praag; Suzanne Jurriaans; Joep M A Lange; Jan M Prins
Journal:  AIDS       Date:  2002-08-16       Impact factor: 4.177

2.  Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. The Swiss HIV Cohort Study.

Authors:  P L Vernazza; L Troiani; M J Flepp; R W Cone; J Schock; F Roth; K Boggian; M S Cohen; S A Fiscus; J J Eron
Journal:  AIDS       Date:  2000-01-28       Impact factor: 4.177

3.  2004 Canadian sexually transmitted infections surveillance report.

Authors: 
Journal:  Can Commun Dis Rep       Date:  2007-05

4.  Association between culturable human immunodeficiency virus type 1 (HIV-1) in semen and HIV-1 RNA levels in semen and blood: evidence for compartmentalization of HIV-1 between semen and blood.

Authors:  R W Coombs; C E Speck; J P Hughes; W Lee; R Sampoleo; S O Ross; J Dragavon; G Peterson; T M Hooton; A C Collier; L Corey; L Koutsky; J N Krieger
Journal:  J Infect Dis       Date:  1998-02       Impact factor: 5.226

5.  Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1. AIDSCAP Malawi Research Group.

Authors:  M S Cohen; I F Hoffman; R A Royce; P Kazembe; J R Dyer; C C Daly; D Zimba; P L Vernazza; M Maida; S A Fiscus; J J Eron
Journal:  Lancet       Date:  1997-06-28       Impact factor: 79.321

6.  Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy.

Authors:  G Dornadula; H Zhang; B VanUitert; J Stern; L Livornese; M J Ingerman; J Witek; R J Kedanis; J Natkin; J DeSimone; R J Pomerantz
Journal:  JAMA       Date:  1999-11-03       Impact factor: 56.272

7.  Human immunodeficiency virus type 1 shedding pattern in semen correlates with the compartmentalization of viral Quasi species between blood and semen.

Authors:  P Gupta; C Leroux; B K Patterson; L Kingsley; C Rinaldo; M Ding; Y Chen; K Kulka; W Buchanan; B McKeon; R Montelaro
Journal:  J Infect Dis       Date:  2000-06-29       Impact factor: 5.226

8.  Adherence to antiretroviral therapy and persistence of HIV RNA in semen.

Authors:  Paulo F Barroso; Mauro Schechter; Phalguni Gupta; Clarisse Bressan; Antonieta Bomfim; Lee H Harrison
Journal:  J Acquir Immune Defic Syndr       Date:  2003-04-01       Impact factor: 3.731

9.  Quantitation of human immunodeficiency virus type 1 RNA loads in cervicovaginal secretions in pregnant women and relationship between viral loads in the genital tract and blood.

Authors:  S García-Bujalance; G Ruiz; C Ladrón De Guevara; J M Peña; I Bates; J J Vázquez; A Gutiérrez
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2004-01-20       Impact factor: 3.267

10.  Correlates of HIV-1 shedding in cervicovaginal secretions and effects of antiretroviral therapies.

Authors:  Josè Ramòn Fiore; Barbara Suligoi; Annalisa Saracino; Mariantonietta Di Stefano; Roberto Bugarini; Achiropita Lepera; Anna Favia; Laura Monno; Gioacchino Angarano; Giuseppe Pastore
Journal:  AIDS       Date:  2003-10-17       Impact factor: 4.177

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  1 in total

1.  Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques.

Authors:  Andre Durudas; Hui-Ling Chen; Melanie A Gasper; Vasudha Sundaravaradan; Jeffrey M Milush; Guido Silvestri; Welkin Johnson; Luis D Giavedoni; Donald L Sodora
Journal:  Curr HIV Res       Date:  2011-07       Impact factor: 1.581

  1 in total

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