Literature DB >> 18614875

Serum alpha-fetoprotein predicts virologic response to hepatitis C treatment in HIV coinfected patients.

Fabrice Carrat1, Pierre Bedossa, Françoise Lunel-Fabiani, Patrice Morand, Gilles Pialoux, Lionel Piroth, Dominique Salmon-Céron, Firouzé Bani-Sadr, Christian Perronne, Patrice Cacoub, Stanislas Pol.   

Abstract

We explored the link between serum alpha-fetoprotein levels and virologic response in 383 HIV-hepatitis C virus coinfected patients. A low alpha-fetoprotein level (<5.0 ng/ml) was an independent predictor of sustained virologic response (odds ratio = 1.83; 95% confidence interval 1.05-3.20). Serum alpha-fetoprotein measurement should be integrated in the pretreatment assessment of prognostic factors of a virologic response.

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Year:  2008        PMID: 18614875     DOI: 10.1097/QAD.0b013e3282f7370d

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  1 in total

1.  Alpha-fetoprotein: a controversial prognostic biomarker for small hepatocellular carcinoma.

Authors:  Mohamed Asrih; Sébastien Lenglet; François Mach; Fabrizio Montecucco
Journal:  World J Gastroenterol       Date:  2013-01-21       Impact factor: 5.742

  1 in total

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