Literature DB >> 18614005

Rab5 and rac team up in cell motility.

Tobias Zech1, Laura Machesky.   

Abstract

Cell motility requires actin assembly mediated by Rac, a Rho family GTPase. In this issue, Palamidessi et al. (2008) show that Rab5-directed trafficking of Rac to the cell membrane is required for Rac-mediated actin assembly. Trafficking of Rac may influence the mode of cell migration during morphogenesis and cancer metastasis.

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Year:  2008        PMID： 18614005     DOI： 10.1016/j.cell.2008.06.039

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  8 in total

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Journal:  Small GTPases       Date:  2015-08-20

Review 2.  Planar cell polarity signaling: the developing cell's compass.

Authors:  Eszter K Vladar; Dragana Antic; Jeffrey D Axelrod
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-09       Impact factor: 10.005

Review 3.  Potential microRNA-related Targets for Therapeutic Intervention with Ovarian Cancer Metastasis.

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Journal:  Cancer Genomics Proteomics       Date:  2018 Jan-Feb       Impact factor: 4.069

Review 4.  Rab GTPases implicated in inherited and acquired disorders.

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Journal:  Semin Cell Dev Biol       Date:  2010-12-13       Impact factor: 7.727

5.  MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer.

Authors:  Yue Zhang; Fu-Jun Zhao; Li-Lan Chen; Luo-Qiao Wang; Kenneth P Nephew; Ying-Li Wu; Shu Zhang
Journal:  Oncotarget       Date:  2014-12-15

6.  LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer.

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Journal:  Mol Med Rep       Date:  2016-07-28       Impact factor: 2.952

7.  Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion.

Authors:  Zhongya Sun; Hao Zhang; Yuanyuan Zhang; Liping Liao; Wen Zhou; Fengcai Zhang; Fulin Lian; Jing Huang; Pan Xu; Rukang Zhang; Wenchao Lu; Mingrui Zhu; Hongru Tao; Feng Yang; Hong Ding; Shijie Chen; Liyan Yue; Bing Zhou; Naixia Zhang; Minjia Tan; Hualiang Jiang; Kaixian Chen; Bo Liu; Chuanpeng Liu; Yongjun Dang; Cheng Luo
Journal:  Adv Sci (Weinh)       Date:  2020-05-13       Impact factor: 16.806

8.  Pathway analysis for genome-wide association study of lung cancer in Han Chinese population.

Authors:  Ruyang Zhang; Yang Zhao; Minjie Chu; Chen Wu; Guangfu Jin; Juncheng Dai; Cheng Wang; Lingmin Hu; Jianwei Gou; Chen Qian; Jianling Bai; Tangchun Wu; Zhibin Hu; Dongxin Lin; Hongbing Shen; Feng Chen
Journal:  PLoS One       Date:  2013-03-01       Impact factor: 3.240
  8 in total

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