Literature DB >> 1861145

Urinary but not brain isatin levels are reduced in germ-free rats.

M Sandler1, A Przyborowska, J Halket, P Watkins, V Glover, M E Coates.   

Abstract

Germ-free rats excreted considerably smaller amounts of the monoamine oxidase-inhibiting compound isatin than the substantially larger output by conventional animals of the same strain, although concentrations in brain and other tissues were similar in the two groups. Thus, isatin is likely to be elaborated both endogenously in rat tissues and "exogenously" by flora inhabiting the lumen of the alimentary tract.

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Year:  1991        PMID: 1861145     DOI: 10.1111/j.1471-4159.1991.tb08259.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN: 0022-3042            Impact factor:   5.372


  5 in total

Review 1.  Tryptophan Metabolites as Mediators of Microbiota-Gut-Brain Communication: Focus on Isatin.

Authors:  Alexei Medvedev; Olga Buneeva
Journal:  Front Behav Neurosci       Date:  2022-06-30       Impact factor: 3.617

2.  Isatin-induced increase in the affinity of human ferrochelatase and adrenodoxin reductase interaction.

Authors:  Pavel Ershov; Yuri Mezentsev; Andrey Gilep; Sergey Usanov; Olga Buneeva; Alexei Medvedev; Alexis Ivanov
Journal:  Protein Sci       Date:  2017-10-09       Impact factor: 6.725

3.  Biological targets for isatin and its analogues: Implications for therapy.

Authors:  Alexei Medvedev; Olga Buneeva; Vivette Glover
Journal:  Biologics       Date:  2007-06

4.  Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: part III - convergence toward clinical trials.

Authors:  Alison C Bested; Alan C Logan; Eva M Selhub
Journal:  Gut Pathog       Date:  2013-03-16       Impact factor: 4.181

5.  A Neuroprotective Dose of Isatin Causes Multilevel Changes Involving the Brain Proteome: Prospects for Further Research.

Authors:  Alexei Medvedev; Arthur Kopylov; Olga Buneeva; Leonid Kurbatov; Olga Tikhonova; Alexis Ivanov; Victor Zgoda
Journal:  Int J Mol Sci       Date:  2020-06-11       Impact factor: 5.923

  5 in total

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