| Literature DB >> 18611036 |
Long Wu1, Shuping Lin, Ding Li.
Abstract
Enoyl-CoA hydratase 1 and enoyl-CoA hydratase 2 in long-chain fatty acid oxidation were comparatively investigated through mechanistic studies for inactivation of the enzymes with methylenecyclopropylformyl-CoA and 3-octynoyl-CoA. Methylenecyclopropylformyl-CoA can inactivate both enzymes, while 3-octynoyl-CoA inactivates enoyl-CoA hydratase 2 only. The study increased our understanding of these two enzymes in fatty acid oxidation.Entities:
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Year: 2008 PMID： 18611036 DOI： 10.1021/ol801267e
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005