| Literature DB >> 18611034 |
Matthew A J Duncton1, M Angels Estiarte, Darlene Tan, Carl Kaub, Donogh J R O'Mahony, Russell J Johnson, Matthew Cox, William T Edwards, Min Wan, John Kincaid, Michael G Kelly.
Abstract
The oxetan-3-yl and azetidin-3-yl substituents have previously been identified as privileged motifs within medicinal chemistry. An efficient approach to installing these two modules into aromatic systems, using a nickel-mediated alkyl-aryl Suzuki coupling, is presented.Entities:
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Year: 2008 PMID： 18611034 DOI： 10.1021/ol8011327
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005