PURPOSE: To provide a clinical tool for calculating a patient's future risk for developing cognitive impairment based on age, family history, and Rey Auditory Verbal Learning Test (AVLT) retention. PARTICIPANTS: 1,019 cognitively normal persons followed for an average of 5 years; 159 participants were eventually diagnosed with cognitive impairment. RESULTS: Risk of developing cognitive impairment increases with age and family history, but decreases with better memory performance. A nomogram is provided for calculation of relative risk of developing cognitive impairment in combinations of age, family history, and memory performance. CONCLUSIONS: These results enhance clinicians' ability to provide information to a patient about risk of cognitive impairment.
PURPOSE: To provide a clinical tool for calculating a patient's future risk for developing cognitive impairment based on age, family history, and Rey Auditory Verbal Learning Test (AVLT) retention. PARTICIPANTS: 1,019 cognitively normal persons followed for an average of 5 years; 159 participants were eventually diagnosed with cognitive impairment. RESULTS: Risk of developing cognitive impairment increases with age and family history, but decreases with better memory performance. A nomogram is provided for calculation of relative risk of developing cognitive impairment in combinations of age, family history, and memory performance. CONCLUSIONS: These results enhance clinicians' ability to provide information to a patient about risk of cognitive impairment.
Authors: S Y Bookheimer; M H Strojwas; M S Cohen; A M Saunders; M A Pericak-Vance; J C Mazziotta; G W Small Journal: N Engl J Med Date: 2000-08-17 Impact factor: 91.245
Authors: R J Killiany; T Gomez-Isla; M Moss; R Kikinis; T Sandor; F Jolesz; R Tanzi; K Jones; B T Hyman; M S Albert Journal: Ann Neurol Date: 2000-04 Impact factor: 10.422
Authors: G C Román; T K Tatemichi; T Erkinjuntti; J L Cummings; J C Masdeu; J H Garcia; L Amaducci; J M Orgogozo; A Brun; A Hofman Journal: Neurology Date: 1993-02 Impact factor: 9.910
Authors: M M Machulda; H A Ward; B Borowski; J L Gunter; R H Cha; P C O'Brien; R C Petersen; B F Boeve; D Knopman; D F Tang-Wai; R J Ivnik; G E Smith; E G Tangalos; C R Jack Journal: Neurology Date: 2003-08-26 Impact factor: 9.910
Authors: Daria A Kashtanova; Anastasiia N Taraskina; Veronika V Erema; Anna A Akopyan; Mikhail V Ivanov; Irina D Strazhesko; Alexandra I Akinshina; Vladimir S Yudin; Valentin V Makarov; Sergey A Kraevoy; Denis E Korolev; Irina V Tarasova; Olga A Beloshevskaya; Elen A Mkhitaryan; Olga N Tkacheva; Sergey M Yudin Journal: Int J Environ Res Public Health Date: 2022-07-04 Impact factor: 4.614