Literature DB >> 18608172

Side effects of second-generation antipsychotics: the experiences, views and monitoring practices of Australian child psychiatrists.

Garry Walter1, Amy DeLaroche, Nerissa Soh, Glenn Hunt, Michelle Cleary, Gin Malhi, Tim Lambert, Christoph Correll, Joseph Rey.   

Abstract

OBJECTIVE: The aim of this study was to ascertain the experiences, views and monitoring practices of Australian child psychiatrists regarding the metabolic and other side effects of second-generation antipsychotics (SGAs).
METHOD: A 19-item questionnaire was posted to all members of the RANZCP Faculty of Child and Adolescent Psychiatry living in Australia.
RESULTS: Of the 290 eligible members of the Faculty of Child and Adolescent Psychiatry, 126 (43%) returned a useable survey. SGAs are commonly prescribed for a range of disorders. The majority of respondents expressed a high level of concern regarding weight gain and other metabolic side effects. Weight gain was the most frequently observed and monitored side effect in clinical practice. Other side effects were observed and monitored to a variable extent. Notably, monitoring practices did not parallel psychiatrists' reported level of concern or knowledge regarding weight gain and metabolic side effects,nor coincide with published recommendations.
CONCLUSIONS: Further research is required into the use, efficacy, side effects and monitoring of SGAs in children and adolescents, and there is a need to ensure that monitoring guidelines are implemented in clinical practice. This need is heightened by the likelihood that our data on clinicians' practice, which is based on their perceptions, may overestimate what actually occurs.

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Year:  2008        PMID: 18608172     DOI: 10.1080/10398560801958549

Source DB:  PubMed          Journal:  Australas Psychiatry        ISSN: 1039-8562            Impact factor:   1.369


  6 in total

1.  First do no harm: promoting an evidence-based approach to atypical antipsychotic use in children and adolescents.

Authors:  Constadina Panagiotopoulos; Rebecca Ronsley; Dean Elbe; Jana Davidson; Derryck H Smith
Journal:  J Can Acad Child Adolesc Psychiatry       Date:  2010-05

2.  Barriers and facilitators to implementation of a metabolic monitoring protocol in hospital and community settings for second-generation antipsychotic-treated youth.

Authors:  Rebecca Ronsley; Kamini Raghuram; Jana Davidson; Constadina Panagiotopoulos
Journal:  J Can Acad Child Adolesc Psychiatry       Date:  2011-05

Review 3.  Childhood obesity and environmental chemicals.

Authors:  Michele La Merrill; Linda S Birnbaum
Journal:  Mt Sinai J Med       Date:  2011 Jan-Feb

4.  Clinicians' views of treatment types for first episode psychosis delivered in a randomised controlled trial (MAPS).

Authors:  Byrne Re; Reeve S; Bird Jc; Jones W; Shiers D; Morrison Ap; Pyle M; Peters S
Journal:  EClinicalMedicine       Date:  2020-07-07

5.  Child and adolescent psychiatrists' reported monitoring behaviors for second-generation antipsychotics.

Authors:  Angie Mae Rodday; Susan K Parsons; Catherine Mankiw; Christoph U Correll; Adelaide S Robb; Bonnie T Zima; Tully S Saunders; Laurel K Leslie
Journal:  J Child Adolesc Psychopharmacol       Date:  2015-04-28       Impact factor: 2.576

6.  Glucose and Prolactin Monitoring in Children and Adolescents Initiating Antipsychotic Therapy.

Authors:  Yasuyuki Okumura; Masahide Usami; Takashi Okada; Takuya Saito; Hideki Negoro; Noa Tsujii; Junichi Fujita; Junzo Iida
Journal:  J Child Adolesc Psychopharmacol       Date:  2018-06-11       Impact factor: 2.576

  6 in total

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