Literature DB >> 18604455

Towards immunotherapeutic drugs and vaccines against multiple sclerosis.

Maria Katsara1, John Matsoukas, George Deraos, Vasso Apostolopoulos.   

Abstract

Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. Numerous treatment options are available to MS patients; however, these options need to be improved. Herein, we review the current drugs and therapeutic approaches available to MS patients, preclinical trial interventions and recent animal model studies for the potential therapy of MS. Since the current treatment of MS remains elusive and is limited, animal studies and clinical research offers an optimistic outlook.

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Year:  2008        PMID: 18604455     DOI: 10.1111/j.1745-7270.2008.00444.x

Source DB:  PubMed          Journal:  Acta Biochim Biophys Sin (Shanghai)        ISSN: 1672-9145            Impact factor:   3.848


  10 in total

1.  Altered peptide ligands of myelin basic protein ( MBP87-99 ) conjugated to reduced mannan modulate immune responses in mice.

Authors:  Maria Katsara; Elizabeth Yuriev; Paul A Ramsland; Theodore Tselios; George Deraos; Athanasios Lourbopoulos; Nikolaos Grigoriadis; John Matsoukas; Vasso Apostolopoulos
Journal:  Immunology       Date:  2009-12       Impact factor: 7.397

Review 2.  Stem cells in clinical practice: applications and warnings.

Authors:  Daniele Lodi; Tommaso Iannitti; Beniamino Palmieri
Journal:  J Exp Clin Cancer Res       Date:  2011-01-17

Review 3.  Targeting antigens to dendritic cell receptors for vaccine development.

Authors:  Vasso Apostolopoulos; Theresia Thalhammer; Andreas G Tzakos; Lily Stojanovska
Journal:  J Drug Deliv       Date:  2013-10-08

4.  Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83-96) Epitope to Function as T-Cell Receptor Antagonists.

Authors:  Mary-Patricia Yannakakis; Carmen Simal; Haralambos Tzoupis; Maria Rodi; Narges Dargahi; Monica Prakash; Athanasia Mouzaki; James A Platts; Vasso Apostolopoulos; Theodore V Tselios
Journal:  Int J Mol Sci       Date:  2017-06-08       Impact factor: 5.923

Review 5.  Multiple Sclerosis: Immunopathology and Treatment Update.

Authors:  Narges Dargahi; Maria Katsara; Theodore Tselios; Maria-Eleni Androutsou; Maximilian de Courten; John Matsoukas; Vasso Apostolopoulos
Journal:  Brain Sci       Date:  2017-07-07

6.  The Long Road of Immunotherapeutics against Multiple Sclerosis.

Authors:  Vasso Apostolopoulos; Abdolmohamad Rostami; John Matsoukas
Journal:  Brain Sci       Date:  2020-05-11

Review 7.  A Global Review on Short Peptides: Frontiers and Perspectives.

Authors:  Vasso Apostolopoulos; Joanna Bojarska; Tsun-Thai Chai; Sherif Elnagdy; Krzysztof Kaczmarek; John Matsoukas; Roger New; Keykavous Parang; Octavio Paredes Lopez; Hamideh Parhiz; Conrad O Perera; Monica Pickholz; Milan Remko; Michele Saviano; Mariusz Skwarczynski; Yefeng Tang; Wojciech M Wolf; Taku Yoshiya; Janusz Zabrocki; Piotr Zielenkiewicz; Maha AlKhazindar; Vanessa Barriga; Konstantinos Kelaidonis; Elham Mousavinezhad Sarasia; Istvan Toth
Journal:  Molecules       Date:  2021-01-15       Impact factor: 4.411

8.  The Human Myelin Proteome and Sub-Metalloproteome Interaction Map: Relevance to Myelin-Related Neurological Diseases.

Authors:  Christos T Chasapis; Konstantinos Kelaidonis; Harry Ridgway; Vasso Apostolopoulos; John M Matsoukas
Journal:  Brain Sci       Date:  2022-03-24

9.  Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System.

Authors:  Graham J Moore; Harry Ridgway; Konstantinos Kelaidonis; Christos T Chasapis; Irene Ligielli; Thomas Mavromoustakos; Joanna Bojarska; John M Matsoukas
Journal:  Molecules       Date:  2022-07-29       Impact factor: 4.927

10.  Diminazene Aceturate Reduces Angiotensin II Constriction and Interacts with the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2.

Authors:  John M Matsoukas; Laura Kate Gadanec; Anthony Zulli; Vasso Apostolopoulos; Konstantinos Kelaidonis; Irene Ligielli; Kalliopi Moschovou; Nikitas Georgiou; Panagiotis Plotas; Christos T Chasapis; Graham Moore; Harry Ridgway; Thomas Mavromoustakos
Journal:  Biomedicines       Date:  2022-07-18
  10 in total

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