Literature DB >> 18602824

Health-promoting effects of bovine colostrum in Type 2 diabetic patients can reduce blood glucose, cholesterol, triglyceride and ketones.

Jun Ho Kim1, Wan Sik Jung, Nag-Jin Choi, Dae-Ok Kim, Dong-Hoon Shin, Young Jun Kim.   

Abstract

Bovine colostrum (BC) has been reported to enhance immune function, reduce fat accumulation and facilitate the movement of glucose to the muscle. However, very few attempts have been made to examine its anti-diabetic effects in diabetes patients. The aim of this study was to evaluate whether BC decreases blood glucose, as well as cholesterol, triglyceride (TG) and ketones levels, which can be elevated by obesity and stress in Type 2 diabetic patients. Sixteen patients (men=8, women=8) with Type 2 diabetes were randomized into the study. Each ingested 5 g of BC on an empty stomach every morning and night for 4 weeks. Blood glucose, ketones (beta-hydroxybutyric acid), total cholesterol and TGs were measured every week. In both the men and women, blood glucose levels at 2 and 8 h postprandial decreased continually during the experimental period. The rate of decrease in blood glucose at 8 h postprandial was not different between the men and women, but was higher in the women (14.25+/-2.66) than in the men (10.96+/-1.82%) at 2 h postprandial. Total cholesterol and TG levels decreased significantly in both the men and women after 4 weeks. Also, beta-hydroxybutyric acid level decreased with BC ingestion, but this was not significant. These results suggest that BC can decrease levels of blood glucose and ketones, as well as reduce cholesterol and TGs, all of which may cause complications in Type 2 diabetic patients.

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Year:  2008        PMID: 18602824     DOI: 10.1016/j.jnutbio.2008.04.002

Source DB:  PubMed          Journal:  J Nutr Biochem        ISSN: 0955-2863            Impact factor:   6.048


  4 in total

1.  Protective effect of whey proteins against nonalcoholic fatty liver in rats.

Authors:  Essam M Hamad; Soad H Taha; Abdel-Gawad I Abou Dawood; Mahmoud Z Sitohy; Mahmoud Abdel-Hamid
Journal:  Lipids Health Dis       Date:  2011-04-13       Impact factor: 3.876

Review 2.  Bovine Colostrum: Its Constituents and Uses.

Authors:  Raymond John Playford; Michael James Weiser
Journal:  Nutrients       Date:  2021-01-18       Impact factor: 5.717

3.  Flos Lonicera ameliorates obesity and associated endotoxemia in rats through modulation of gut permeability and intestinal microbiota.

Authors:  Jing-Hua Wang; Shambhunath Bose; Gi-Cheol Kim; Seung-Ug Hong; Ji-Hun Kim; Jai-Eun Kim; Hojun Kim
Journal:  PLoS One       Date:  2014-01-24       Impact factor: 3.240

Review 4.  Production of Bovine Colostrum for Human Consumption to Improve Health.

Authors:  Merve Kaplan; Ayşenur Arslan; Hatice Duman; Melda Karyelioğlu; Barış Baydemir; Bilgetekin Burak Günar; Merve Alkan; Ayşe Bayraktar; Halil İbrahim Tosun; Melih Ertürk; Günay Eskici; Rebbeca M Duar; Bethany M Henrick; Steven A Frese; Sercan Karav
Journal:  Front Pharmacol       Date:  2022-01-03       Impact factor: 5.810

  4 in total

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