Literature DB >> 18602445

Fine-mapping at the HTR2A locus reveals multiple episodic memory-related variants.

Jessica C Sigmund1, Christian Vogler, Kim-Dung Huynh, Dominique J-F de Quervain, Andreas Papassotiropoulos.   

Abstract

A functional polymorphism (His452Tyr) in the gene encoding the serotonin 2A receptor (HTR2A) has been previously associated with human episodic memory performance and with differences in brain volume in memory-related brain regions. Here we present data obtained through imputation and fine-mapping showing that multiple loci within HTR2A are significantly associated with human memory performance independently of the His452Tyr polymorphism. Our data support the existence of multiple memory-related loci within HTR2A.

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Year:  2008        PMID： 18602445     DOI： 10.1016/j.biopsycho.2008.06.002

Source DB:  PubMed          Journal:  Biol Psychol        ISSN： 0301-0511            Impact factor:   3.251


  10 in total

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2.  K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.

Authors:  Roman M Stilling; Raik Rönicke; Eva Benito; Hendrik Urbanke; Vincenzo Capece; Susanne Burkhardt; Sanaz Bahari-Javan; Jonas Barth; Farahnaz Sananbenesi; Anna L Schütz; Jerzy Dyczkowski; Ana Martinez-Hernandez; Cemil Kerimoglu; Sharon Y R Dent; Stefan Bonn; Klaus G Reymann; Andre Fischer
Journal:  EMBO J       Date:  2014-07-14       Impact factor: 11.598

3.  Blockade of 5-HT2 receptor selectively prevents MDMA-induced verbal memory impairment.

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4.  Polymorphism of serotonin receptor genes (5-HTR2A) and Dysbindin (DTNBP1) and individual components of short-term verbal memory processes in Schizophrenia.

Authors:  M V Alfimova; M V Monakhov; L I Abramova; S A Golubev; V E Golimbet
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5.  Associations between catecholaminergic, GABAergic, and serotonergic genes and self-reported attentional function in oncology patients and their family caregivers.

Authors:  John D Merriman; Bradley E Aouizerat; Janine K Cataldo; Laura B Dunn; Kord Kober; Dale J Langford; Claudia West; Bruce A Cooper; Steven M Paul; Christine Miaskowski
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6.  A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

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Review 7.  Genetics of cognition in epilepsy.

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Review 8.  The role of serotonin 5-HT2A receptors in memory and cognition.

Authors:  Gongliang Zhang; Robert W Stackman
Journal:  Front Pharmacol       Date:  2015-10-06       Impact factor: 5.810

9.  Serotonin 2a Receptor and Serotonin 1a Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice.

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  10 in total

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