Literature DB >> 18600360

Life-threatening bite injury of the lower lip after use of metamizole.

S T Becker1, J Wiltfang, I N Springer, M S Bartsch, R Guenther, E Sherry, P H Warnke.   

Abstract

INTRODUCTION: Bite wounds of the oral mucosa heal after eliminating the causative irritant, but there are serious exceptions from the rule. We present the case of a 37-year-old woman with an ulcer of the mucosa of the lower lip, which had been present for 10 days, and leucopenia. DISCUSSION: Agranulocytosis after the use of metamizole is part from leukaemia and lues, a rare reason for non-healing ulcers of the mucosa of the oral cavity without fulminant signs for inflammation.
CONCLUSION: As this is a life-threatening disease, medical therapy must begin immediately.

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Year:  2008        PMID: 18600360     DOI: 10.1007/s10006-008-0099-3

Source DB:  PubMed          Journal:  Oral Maxillofac Surg        ISSN: 1865-1550


  12 in total

Review 1.  Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features.

Authors:  A E Singh; B Romanowski
Journal:  Clin Microbiol Rev       Date:  1999-04       Impact factor: 26.132

2.  Dipyrone and agranulocytosis: what is the risk?

Authors:  Jayne E Edwards; Henry J McQuay
Journal:  Lancet       Date:  2002-11-09       Impact factor: 79.321

3.  Dipyrone and agranulocytosis: what is the risk?

Authors:  Peter Schönhöfer; Leo Offerhaus; Andrew Herxheimer
Journal:  Lancet       Date:  2003-03-15       Impact factor: 79.321

4.  Agranulocytosis and dipyrone.

Authors:  V Vlahov; N Bacracheva
Journal:  Lancet       Date:  1989-11-18       Impact factor: 79.321

Review 5.  Syphilis.

Authors:  D M Musher
Journal:  Infect Dis Clin North Am       Date:  1987-03       Impact factor: 5.982

6.  Safety of dipyrone.

Authors:  M Levy; S Shapiro
Journal:  Lancet       Date:  1986-11-01       Impact factor: 79.321

7.  Antibacterial essential oils in malodorous cancer patients: clinical observations in 30 patients.

Authors:  P H Warnke; E Sherry; P A J Russo; Y Açil; J Wiltfang; S Sivananthan; M Sprengel; J C Roldàn; S Schubert; J P Bredee; I N G Springer
Journal:  Phytomedicine       Date:  2005-11-02       Impact factor: 5.340

8.  Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.

Authors: 
Journal:  JAMA       Date:  1986-10-03       Impact factor: 56.272

9.  Agranulocytosis and other blood dyscrasias associated with dipyrone (metamizole).

Authors:  Karin Hedenmalm; Olav Spigset
Journal:  Eur J Clin Pharmacol       Date:  2002-06-06       Impact factor: 2.953

10.  Acute gingival necrosis caused by drug-induced agranulocytosis.

Authors:  M Ohishi; K Oobu; Y Miyanoshita; K Yamaguchi
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1988-08
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