Literature DB >> 18600103

Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.

Kenichi A Tanaka, Andras Gruber, Fania Szlam, Leslie A Bush, Stephen R Hanson, Enrico Di Cera.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18600103      PMCID： PMC2706698          DOI： 10.1097/MBC.0b013e328304e044

Source DB:  PubMed          Journal:  Blood Coagul Fibrinolysis        ISSN： 0957-5235            Impact factor:   1.276


× No keyword cloud information.
  13 in total

1.  An extensive interaction interface between thrombin and factor V is required for factor V activation.

Authors:  T Myles; T H Yun; S W Hall; L L Leung
Journal:  J Biol Chem       Date:  2001-04-18       Impact factor: 5.157

2.  Dissecting substrate recognition by thrombin using the inactive mutant S195A.

Authors:  Maxwell M Krem; Enrico Di Cera
Journal:  Biophys Chem       Date:  2003       Impact factor: 2.352

3.  Influence of bivalirudin on tissue factor-triggered coagulation.

Authors:  Saulius Butenas; Thomas Orfeo; Kathleen E Brummel-Ziedins; Kenneth G Mann
Journal:  Blood Coagul Fibrinolysis       Date:  2007-07       Impact factor: 1.276

4.  The effects of argatroban on thrombin generation and hemostatic activation in vitro.

Authors:  Kenichi A Tanaka; Fania Szlam; Nobuyuki Katori; Nobukazu Sato; J David Vega; Jerrold H Levy
Journal:  Anesth Analg       Date:  2004-11       Impact factor: 5.108

5.  Rational design of a potent anticoagulant thrombin.

Authors:  A M Cantwell; E Di Cera
Journal:  J Biol Chem       Date:  2000-12-22       Impact factor: 5.157

6.  The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket.

Authors:  Agustin O Pineda; Zhi-Wei Chen; Sonia Caccia; Angelene M Cantwell; Savvas N Savvides; Gabriel Waksman; F Scott Mathews; Enrico Di Cera
Journal:  J Biol Chem       Date:  2004-07-13       Impact factor: 5.157

7.  Calibrated automated thrombin generation measurement in clotting plasma.

Authors:  H Coenraad Hemker; Peter Giesen; Raed Al Dieri; Véronique Regnault; Eric de Smedt; Rob Wagenvoord; Thomas Lecompte; Suzette Béguin
Journal:  Pathophysiol Haemost Thromb       Date:  2003

8.  The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo.

Authors:  Andras Gruber; Angelene M Cantwell; Enrico Di Cera; Stephen R Hanson
Journal:  J Biol Chem       Date:  2002-06-17       Impact factor: 5.157

9.  Predicting the pharmacology of thrombin inhibitors.

Authors:  T E Adams; S J Everse; K G Mann
Journal:  J Thromb Haemost       Date:  2003-05       Impact factor: 5.824

10.  A critical role for thrombin in platelet aggregation under high shear stress.

Authors:  Yoshihiko Sakurai; Midori Shima; John Giddings; Masahiro Takeyama; Shogo Kasuda; Keiji Nogami; Katsumi Nishiya; Akira Yoshioka
Journal:  Thromb Res       Date:  2004       Impact factor: 3.944
View more
  2 in total

1.  Stabilization of the E* form turns thrombin into an anticoagulant.

Authors:  Alaji Bah; Christopher J Carrell; Zhiwei Chen; Prafull S Gandhi; Enrico Di Cera
Journal:  J Biol Chem       Date:  2009-05-27       Impact factor: 5.157

2.  How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen.

Authors:  Riley B Peacock; Taylor McGrann; Sofia Zaragoza; Elizabeth A Komives
Journal:  Biochemistry       Date:  2022-01-03       Impact factor: 3.321
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.