Literature DB >> 18598938

Deregulating EMT and senescence: double impact by a single twist.

Marjon A Smit1, Daniel S Peeper.   

Abstract

The acquisition of a fully malignant phenotype is limited by several barriers, including cellular senescence and the requirement to undergo an epithelial-mesenchymal transition (EMT). Deregulation of these processes is believed to occur by largely independent events. In this issue of Cancer Cell, Ansieau et al. (2008) challenge this view.

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Year:  2008        PMID： 18598938     DOI： 10.1016/j.ccr.2008.06.012

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  31 in total

1.  Mutational analysis of Mdm2 C-terminal tail suggests an evolutionarily conserved role of its length in Mdm2 activity toward p53 and indicates structural differences between Mdm2 homodimers and Mdm2/MdmX heterodimers.

Authors:  Pavlina Dolezelova; Katerina Cetkovska; Karen H Vousden; Stjepan Uldrijan
Journal:  Cell Cycle       Date:  2012-03-01       Impact factor: 4.534

Review 2.  Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer.

Authors:  Nicole Vincent Jordan; Gary L Johnson; Amy N Abell
Journal:  Cell Cycle       Date:  2011-09-01       Impact factor: 4.534

3.  CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation.

Authors:  Aldo M Roccaro; Yuji Mishima; Antonio Sacco; Michele Moschetta; Yu-Tzu Tai; Jiantao Shi; Yong Zhang; Michaela R Reagan; Daisy Huynh; Yawara Kawano; Ilyas Sahin; Marco Chiarini; Salomon Manier; Michele Cea; Yosra Aljawai; Siobhan Glavey; Elizabeth Morgan; Chin Pan; Franziska Michor; Pina Cardarelli; Michelle Kuhne; Irene M Ghobrial
Journal:  Cell Rep       Date:  2015-07-16       Impact factor: 9.423

4.  Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells.

Authors:  Debasis Nayak; Anmol Kumar; Souneek Chakraborty; Reyaz Ur Rasool; Hina Amin; Archana Katoch; Veena Gopinath; Vidushi Mahajan; Mahesh K Zilla; Bilal Rah; Sumit G Gandhi; Asif Ali; Lekha Dinesh Kumar; Anindya Goswami
Journal:  Cell Death Differ       Date:  2017-05-12       Impact factor: 15.828

5.  Paeonol attenuates aging MRC-5 cells and inhibits epithelial-mesenchymal transition of premalignant HaCaT cells induced by aging MRC-5 cell-conditioned medium.

Authors:  Lihua Yang; Shangping Xing; Kun Wang; Hua Yi; Biaoyan Du
Journal:  Mol Cell Biochem       Date:  2017-08-12       Impact factor: 3.396

6.  Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition.

Authors:  Philip Martin; Yen-Nien Liu; Rachel Pierce; Wassim Abou-Kheir; Orla Casey; Victoria Seng; Daniel Camacho; R Mark Simpson; Kathleen Kelly
Journal:  Am J Pathol       Date:  2011-05-13       Impact factor: 4.307

7.  Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

Authors:  Szu-Wei Lee; Chien-Feng Li; Chia-Hsin Chan; Jing Wang; Wei-Lei Yang; Ching-Yuan Wu; Juan Wu; Keiichi I Nakayama; Hong-Yo Kang; Hsuan-Ying Huang; Mien-Chie Hung; Pier Paolo Pandolfi; Hui-Kuan Lin
Journal:  Nat Cell Biol       Date:  2010-04-11       Impact factor: 28.824

8.  Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions.

Authors:  Alejandro Vazquez-Martin; Eugeni López-Bonetc; Sílvia Cufí; Cristina Oliveras-Ferraros; Sonia Del Barco; Begoña Martin-Castillo; Javier A Menendez
Journal:  Drug Resist Updat       Date:  2011-05-19       Impact factor: 18.500

9.  Epithelial-mesenchymal transition and senescence: two cancer-related processes are crossing paths.

Authors:  Marjon A Smit; Daniel S Peeper
Journal:  Aging (Albany NY)       Date:  2010-10       Impact factor: 5.682

10.  Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9.

Authors:  Dengfeng Cao; Kornelia Polyak; Marc K Halushka; Hind Nassar; Nina Kouprina; Christine Iacobuzio-Donahue; Xinyan Wu; Saraswati Sukumar; Jessica Hicks; Angelo De Marzo; Pedram Argani
Journal:  Breast Cancer Res       Date:  2008-10-27       Impact factor: 6.466
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