Literature DB >> 18594731

Substrate mediated reduction of copper-amyloid-beta complex in Alzheimer's disease.

Victor A Streltsov1, Joseph N Varghese.   

Abstract

X-Ray absorption near-edge spectroscopy (XANES) has been used to probe the substrate mediated reduction of Cu(2+) in Abeta-Cu(2+) complexes by ascorbate and the neurotoxin 6-hydroxydopamine (6-OHDA), however dopamine and, in particular, cholesterol are incapable of reducing soluble monomeric Abeta-Cu(2+) complexes.

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Year:  2008        PMID: 18594731     DOI: 10.1039/b803911a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  6 in total

1.  Structural studies of copper(I) complexes of amyloid-beta peptide fragments: formation of two-coordinate bis(histidine) complexes.

Authors:  Richard A Himes; Ga Young Park; Gnana Sutha Siluvai; Ninian J Blackburn; Kenneth D Karlin
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

2.  Importance of dynamical processes in the coordination chemistry and redox conversion of copper amyloid-beta complexes.

Authors:  Christelle Hureau; Véronique Balland; Yannick Coppel; Pier Lorenzo Solari; Emiliano Fonda; Peter Faller
Journal:  J Biol Inorg Chem       Date:  2009-07-18       Impact factor: 3.358

3.  Mixed monolayers of ferrocenylalkanethiol and encapsulated horseradish peroxidase for sensitive and durable electrochemical detection of hydrogen peroxide.

Authors:  Yong Peng; Dianlu Jiang; Lei Su; Lin Zhang; Ming Yan; Juanjuan Du; Yunfeng Lu; You-Nian Liu; Feimeng Zhou
Journal:  Anal Chem       Date:  2009-12-15       Impact factor: 6.986

4.  The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.

Authors:  Victor A Streltsov; Stephen J Titmuss; V Chandana Epa; Kevin J Barnham; Colin L Masters; Joseph N Varghese
Journal:  Biophys J       Date:  2008-07-03       Impact factor: 4.033

5.  The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptide.

Authors:  Jason Shearer; Veronika A Szalai
Journal:  J Am Chem Soc       Date:  2008-12-31       Impact factor: 15.419

6.  Alkemio: association of chemicals with biomedical topics by text and data mining.

Authors:  José A Gijón-Correas; Miguel A Andrade-Navarro; Jean F Fontaine
Journal:  Nucleic Acids Res       Date:  2014-05-16       Impact factor: 16.971

  6 in total

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