Literature DB >> 18594286

Outbreaks of nosocomial infections: lessons learned and perspectives.

Petra Gastmeier1, Ralf-Peter Vonberg.   

Abstract

PURPOSE OF REVIEW: The review summarizes the results of selected outbreak reports and systematic analyses of nosocomial outbreaks from 2007 and focuses on different aspects of hospital epidemiology and infection control. RECENT
FINDINGS: A single outbreak report is likely be influenced by the local setting. In contrast, a systematic analysis of a large number of similar outbreaks draws a much better picture of the real conditions on the pathogen's reservoirs, on modes of transmission, and on appropriate infection control measures to prevent the spread of the microorganism. Isolation, unit closures, sick leave, cleaning, and diagnostic/therapeutic measures may lead to enormous costs during an outbreak. Thus, cost calculations of outbreaks should be performed to justify future expenses for infection control. Mathematic modeling is a fairly new approach to estimate the risk of pathogen transmission in outbreak settings. Examples are shown to differentiate between epidemic and sporadic infections and to evaluate the influence of infection control interventions.
SUMMARY: Outbreak reports may add some very important information to the understanding of transmission and infection control. There is a need for a more structured publication of nosocomial outbreaks to ensure that no key data are lacking in the article.

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Mesh:

Year:  2008        PMID: 18594286     DOI: 10.1097/QCO.0b013e3283013933

Source DB:  PubMed          Journal:  Curr Opin Infect Dis        ISSN: 0951-7375            Impact factor:   4.915


  6 in total

1.  A social network of hospital acquired infection built from electronic medical record data.

Authors:  Marco Cusumano-Towner; Daniel Y Li; Shanshan Tuo; Gomathi Krishnan; David M Maslove
Journal:  J Am Med Inform Assoc       Date:  2013-03-06       Impact factor: 4.497

2.  Clustering of antimicrobial resistance outbreaks across bacterial species in the intensive care unit.

Authors:  Anne L M Vlek; Ben S Cooper; Theodore Kypraios; Andy Cox; Jonathan D Edgeworth; Olga Tosas Auguet
Journal:  Clin Infect Dis       Date:  2013-04-02       Impact factor: 9.079

3.  A multiplicative hazard regression model to assess the risk of disease transmission at hospital during community epidemics.

Authors:  Nicolas Voirin; Sylvain Roche; Philippe Vanhems; Marine Giard; Sandra David-Tchouda; Béatrice Barret; René Ecochard
Journal:  BMC Med Res Methodol       Date:  2011-04-20       Impact factor: 4.615

4.  Importance of Multifaceted Approaches in Infection Control: A Practical Experience from an Outbreak Investigation.

Authors:  Nina Katharina Stock; Petr Petráš; Oto Melter; Gabriela Kapounová; Petra Vopalková; Jan Kubele; Václav Vaniš; Jan Tkadlec; Eva Bukáčková; Ivana Machová; Vlastimil Jindrák
Journal:  PLoS One       Date:  2016-06-20       Impact factor: 3.240

Review 5.  Worldwide Outbreak Database: the largest collection of nosocomial outbreaks.

Authors:  R-P Vonberg; D Weitzel-Kage; M Behnke; P Gastmeier
Journal:  Infection       Date:  2010-12-03       Impact factor: 3.553

6.  Mobile elements, zoonotic pathogens and commensal bacteria: conduits for the delivery of resistance genes into humans, production animals and soil microbiota.

Authors:  Steven P Djordjevic; Harold W Stokes; Piklu Roy Chowdhury
Journal:  Front Microbiol       Date:  2013-04-30       Impact factor: 5.640

  6 in total

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