Literature DB >> 18591969

Opposing roles for glypicans in Hedgehog signalling.

Dong Yan1, Xinhua Lin.   

Abstract

Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those involving Hedgehog, Wnt, BMP and FGF. Two studies reveal opposite effects of glypicans on Hedgehog signalling and show how their core protein domains and GPI anchor contribute to their versatile biological functions.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18591969     DOI： 10.1038/ncb0708-761

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  13 in total

Review 1.  Shaping morphogen gradients by proteoglycans.

Authors:  Dong Yan; Xinhua Lin
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-09       Impact factor: 10.005

Review 2.  Interactions between Hedgehog proteins and their binding partners come into view.

Authors:  Philip A Beachy; Sarah G Hymowitz; Robert A Lazarus; Daniel J Leahy; Christian Siebold
Journal:  Genes Dev       Date:  2010-09-15       Impact factor: 11.361

3.  Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells.

Authors:  Michael P O'Connell; Jennifer L Fiori; Emily K Kershner; Brittany P Frank; Fred E Indig; Dennis D Taub; Keith S Hoek; Ashani T Weeraratna
Journal:  J Biol Chem       Date:  2009-08-20       Impact factor: 5.157

4.  Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene.

Authors:  Shuang Cui; Melissa Leyva-Vega; Ellen A Tsai; Steven F EauClaire; Joseph T Glessner; Hakon Hakonarson; Marcella Devoto; Barbara A Haber; Nancy B Spinner; Randolph P Matthews
Journal:  Gastroenterology       Date:  2013-01-18       Impact factor: 22.682

5.  Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.

Authors:  Rochelle M Witt; Marie-Lyn Hecht; Maria F Pazyra-Murphy; Samuel M Cohen; Christian Noti; Toin H van Kuppevelt; Maria Fuller; Jennifer A Chan; John J Hopwood; Peter H Seeberger; Rosalind A Segal
Journal:  J Biol Chem       Date:  2013-07-18       Impact factor: 5.157

6.  The core protein of glypican Dally-like determines its biphasic activity in wingless morphogen signaling.

Authors:  Dong Yan; Yihui Wu; Ying Feng; Sheng-Cai Lin; Xinhua Lin
Journal:  Dev Cell       Date:  2009-10       Impact factor: 12.270

7.  The Caenorhabditis elegans Ephrin EFN-4 Functions Non-cell Autonomously with Heparan Sulfate Proteoglycans to Promote Axon Outgrowth and Branching.

Authors:  Alicia A Schwieterman; Alyse N Steves; Vivian Yee; Cory J Donelson; Melissa R Bentley; Elise M Santorella; Taylor V Mehlenbacher; Aaron Pital; Austin M Howard; Melissa R Wilson; Danielle E Ereddia; Kelsie S Effrein; Jonathan L McMurry; Brian D Ackley; Andrew D Chisholm; Martin L Hudson
Journal:  Genetics       Date:  2015-12-08       Impact factor: 4.562

Review 8.  Structural and functional hepatocyte polarity and liver disease.

Authors:  Paul Gissen; Irwin M Arias
Journal:  J Hepatol       Date:  2015-06-24       Impact factor: 25.083

9.  Inactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects.

Authors:  Pan Ma; Wenjuan Yan; Ye Tian; Jingya Wang; Jian Q Feng; Chunlin Qin; Yi-Shing Lisa Cheng; Xiaofang Wang
Journal:  Sci Rep       Date:  2016-07-13       Impact factor: 4.379

10.  Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates.

Authors:  Benjamin Mattes; Yonglong Dang; Gediminas Greicius; Lilian Tamara Kaufmann; Benedikt Prunsche; Jakob Rosenbauer; Johannes Stegmaier; Ralf Mikut; Suat Özbek; Gerd Ulrich Nienhaus; Alexander Schug; David M Virshup; Steffen Scholpp
Journal:  Elife       Date:  2018-07-31       Impact factor: 8.140
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.