Literature DB >> 18591966

Cdh1: a master G0/G1 regulator.

Jeffrey R Skaar1, Michele Pagano.   

Abstract

APC/C(Cdh1) controls the G0 and G1 phases of the cell cycle. Using a conditional knockout of the Cdh1 coding gene Fizzy-related (Fzr), a new study demonstrates that Cdh1 is essential for viability and that it functions as a tumour suppressor by preventing genomic instability.

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Year:  2008        PMID： 18591966      PMCID： PMC2730193          DOI： 10.1038/ncb0708-755

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

Review 1.  Ubiquitin ligases: cell-cycle control and cancer.

Authors:  Keiichi I Nakayama; Keiko Nakayama
Journal:  Nat Rev Cancer       Date:  2006-05       Impact factor: 60.716

Review 2.  Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.

Authors:  Steven I Reed
Journal:  Nat Rev Mol Cell Biol       Date:  2003-11       Impact factor: 94.444

Review 3.  The anaphase-promoting complex/cyclosome: APC/C.

Authors:  Claire Acquaviva; Jonathon Pines
Journal:  J Cell Sci       Date:  2006-06-15       Impact factor: 5.285

Review 4.  Thinking within the D box: initial identification of Cdh1-APC substrates in the nervous system.

Authors:  Albert H Kim; Azad Bonni
Journal:  Mol Cell Neurosci       Date:  2007-01-12       Impact factor: 4.314

5.  Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.

Authors:  Jian-Hua Mao; Jesus Perez-Losada; Di Wu; Reyno Delrosario; Ryosuke Tsunematsu; Keiichi I Nakayama; Ken Brown; Sheila Bryson; Allan Balmain
Journal:  Nature       Date:  2004-12-09       Impact factor: 49.962

6.  fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen.

Authors:  David S Fay; Sean Keenan; Min Han
Journal:  Genes Dev       Date:  2002-02-15       Impact factor: 11.361

7.  The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells.

Authors:  D Engelbert; D Schnerch; A Baumgarten; R Wäsch
Journal:  Oncogene       Date:  2007-08-13       Impact factor: 9.867

8.  Genomic stability and tumour suppression by the APC/C cofactor Cdh1.

Authors:  Irene García-Higuera; Eusebio Manchado; Pierre Dubus; Marta Cañamero; Juan Méndez; Sergio Moreno; Marcos Malumbres
Journal:  Nat Cell Biol       Date:  2008-06-15       Impact factor: 28.824

9.  Completion of mitosis requires neither fzr/rap nor fzr2, a male germline-specific Drosophila Cdh1 homolog.

Authors:  Henning Jacobs; David Richter; Tadmiri Venkatesh; Christian Lehner
Journal:  Curr Biol       Date:  2002-08-20       Impact factor: 10.834

10.  APC/C--the master controller of origin licensing?

Authors:  Umasundari Sivaprasad; Yuichi J Machida; Anindya Dutta
Journal:  Cell Div       Date:  2007-02-23       Impact factor: 5.130
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  35 in total

Review 1.  Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle.

Authors:  Xiomaris M Cotto-Rios; Mathew J K Jones; Tony T Huang
Journal:  Cell Cycle       Date:  2011-12-01       Impact factor: 4.534

2.  Process-based network decomposition reveals backbone motif structure.

Authors:  Guanyu Wang; Chenghang Du; Hao Chen; Rahul Simha; Yongwu Rong; Yi Xiao; Chen Zeng
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-24       Impact factor: 11.205

3.  The role of APC/C(Cdh1) in replication stress and origin of genomic instability.

Authors:  C Greil; J Krohs; D Schnerch; M Follo; J Felthaus; M Engelhardt; R Wäsch
Journal:  Oncogene       Date:  2015-10-12       Impact factor: 9.867

4.  FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia.

Authors:  Jo Ishizawa; Eiji Sugihara; Shinji Kuninaka; Kaoru Mogushi; Kensuke Kojima; Christopher B Benton; Ran Zhao; Dhruv Chachad; Norisato Hashimoto; Rodrigo O Jacamo; Yihua Qiu; Suk Young Yoo; Shinichiro Okamoto; Michael Andreeff; Steven M Kornblau; Hideyuki Saya
Journal:  Blood       Date:  2017-01-31       Impact factor: 22.113

5.  APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit.

Authors:  Zhen Ping; Ratna Lim; Tarig Bashir; Michele Pagano; Daniele Guardavaccaro
Journal:  Cell Cycle       Date:  2012-05-15       Impact factor: 4.534

Review 6.  State of the APC/C: organization, function, and structure.

Authors:  Janel R McLean; Denis Chaix; Melanie D Ohi; Kathleen L Gould
Journal:  Crit Rev Biochem Mol Biol       Date:  2011-01-24       Impact factor: 8.250

Review 7.  Two-way communication between the metabolic and cell cycle machineries: the molecular basis.

Authors:  Joanna Kaplon; Loes van Dam; Daniel Peeper
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

8.  Inhibition of neddylation causes meiotic arrest in mouse oocyte.

Authors:  Mo Yang; Yimei Jin; Siying Fan; Xiaoling Liang; Jialin Jia; Zhongzhou Tan; Tao Huang; Yuan Li; Teng Ma; Mo Li
Journal:  Cell Cycle       Date:  2019-05-21       Impact factor: 4.534

9.  APC/CCdh1 regulates the balance between maintenance and differentiation of hematopoietic stem and progenitor cells.

Authors:  Daniel Ewerth; Stefanie Kreutmair; Andrea Schmidts; Gabriele Ihorst; Marie Follo; Dagmar Wider; Julia Felthaus; Julia Schüler; Justus Duyster; Anna Lena Illert; Monika Engelhardt; Ralph Wäsch
Journal:  Cell Mol Life Sci       Date:  2018-10-24       Impact factor: 9.261

10.  Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.

Authors:  Alan W Lau; Hiroyuki Inuzuka; Hidefumi Fukushima; Lixin Wan; Pengda Liu; Daming Gao; Yi Sun; Wenyi Wei
Journal:  Cell Res       Date:  2013-05-14       Impact factor: 25.617
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