Literature DB >> 18591840

Clinical relevance of sputum cytology and chest X-ray in patients with suspected lung tumors.

Mitsuhiro Sumitani1, Nobuhide Takifuji, Shigeki Nanjyo, Yumiko Imahashi, Hidemi Kiyota, Koji Takeda, Ryoji Yamamoto, Hirohito Tada.   

Abstract

OBJECTIVE: To review diagnostic procedures, therapeutic modalities, and follow-up methods in patients with suspected lung tumors.
METHODS: We retrospectively examined 70 patients who underwent a complete medical checkup because they had been positive for sputum cytology and had presented no chest X-ray findings for the 10-year period between 1994 and 2004. To make a diagnosis, we conducted the first complete medical checkup that included chest X-ray, sputum cytology, chest computed tomography (CT), and bronchoscopy. In the case that no diagnosis could be made, we repeated the chest X-ray and sputum cytology every 3 to 6 months and additionally conducted chest CT and bronchoscopy according to abnormal findings.
RESULTS: Among 70 patients, there were 36 and 13 who were diagnosed during the first complete medical checkup and follow-up, respectively, 13 who remained undiagnosed, and eight for whom follow-up was discontinued. Among the 49 diagnosed patients, 40, 8, and 1 patient had lung cancer, upper respiratory tract carcinoma (URTC), and esophageal carcinoma (EC), respectively. Among the 40 patients with lung cancer, 34 had a stage 0 or I tumor and 15 were radically treatable by photodynamic therapy and endobronchial irradiation. Nine among 11 patients whose lung cancer was detected during follow-up had a stage 0 or IA tumor.
CONCLUSION: Not only lung cancer but also URTC and EC were successfully detected in patients who were positive for sputum cytology and presented negative chest X-ray. Radical treatment was possible in 38 (76%) of 50 diagnosed patients, thus indicating the importance of follow-up through these procedures.

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Year:  2008        PMID: 18591840     DOI: 10.2169/internalmedicine.47.0777

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  4 in total

1.  LncRNA LINC00520 Predicts Poor Prognosis and Promotes Progression of Lung Cancer by Inhibiting MiR-3175 Expression.

Authors:  Gaowei Xia; Xiaoling Li; Fuhui Chen; Zhenyu Shao
Journal:  Cancer Manag Res       Date:  2020-07-17       Impact factor: 3.989

2.  Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study.

Authors:  Jun Maeda; Masahiko Higashiyama; Akira Imaizumi; Tomio Nakayama; Hiroshi Yamamoto; Takashi Daimon; Minoru Yamakado; Fumio Imamura; Ken Kodama
Journal:  BMC Cancer       Date:  2010-12-22       Impact factor: 4.430

3.  Sputum cytology in suspected cases of carcinoma of lung (Sputum cytology a poor man's bronchoscopy!).

Authors:  A S Ammanagi; V D Dombale; A T Miskin; G L Dandagi; S S Sangolli
Journal:  Lung India       Date:  2012-01

4.  The significance and robustness of a plasma free amino acid (PFAA) profile-based multiplex function for detecting lung cancer.

Authors:  Masato Shingyoji; Toshihiko Iizasa; Masahiko Higashiyama; Fumio Imamura; Nobuhiro Saruki; Akira Imaizumi; Hiroshi Yamamoto; Takashi Daimon; Osamu Tochikubo; Toru Mitsushima; Minoru Yamakado; Hideki Kimura
Journal:  BMC Cancer       Date:  2013-02-15       Impact factor: 4.430

  4 in total

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