Literature DB >> 18590687

The double life of Irs.

Rebecca A Haeusler1, Domenico Accili.   

Abstract

The liver plays a central role in lipid and glucose metabolism. Two studies in this issue (Kubota et al., 2008; Dong et al., 2008) on the insulin-signaling adaptors Irs1 and Irs2 prompt a critical reappraisal of the physiology of fasting and of the integrated control of hepatic insulin action.

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Year:  2008        PMID： 18590687      PMCID： PMC2712626          DOI： 10.1016/j.cmet.2008.06.010

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  11 in total

1.  High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO.

Authors:  Boris Gershman; Oscar Puig; Lilian Hang; Robert M Peitzsch; Marc Tatar; Robert S Garofalo
Journal:  Physiol Genomics       Date:  2006-11-07       Impact factor: 3.107

2.  Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.

Authors:  Naoto Kubota; Tetsuya Kubota; Shinsuke Itoh; Hiroki Kumagai; Hideki Kozono; Iseki Takamoto; Tomoka Mineyama; Hitomi Ogata; Kumpei Tokuyama; Mitsuru Ohsugi; Takayoshi Sasako; Masao Moroi; Kaoru Sugi; Shigeru Kakuta; Yoichiro Iwakura; Tetsuo Noda; Shin Ohnishi; Ryozo Nagai; Kazuyuki Tobe; Yasuo Terauchi; Kohjiro Ueki; Takashi Kadowaki
Journal:  Cell Metab       Date:  2008-07       Impact factor: 27.287

Review 3.  Free fatty acids and pathogenesis of type 2 diabetes mellitus.

Authors:  R N Bergman; M Ader
Journal:  Trends Endocrinol Metab       Date:  2000-11       Impact factor: 12.015

4.  Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c).

Authors:  Louis Monnier; Hélène Lapinski; Claude Colette
Journal:  Diabetes Care       Date:  2003-03       Impact factor: 19.112

5.  Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

Authors:  Michihiro Matsumoto; Alessandro Pocai; Luciano Rossetti; Ronald A Depinho; Domenico Accili
Journal:  Cell Metab       Date:  2007-09       Impact factor: 27.287

6.  Insulin signaling in health and disease.

Authors:  Morris F White
Journal:  Science       Date:  2003-12-05       Impact factor: 47.728

7.  Isolated impaired fasting glucose and peripheral insulin sensitivity: not a simple relationship.

Authors:  Sun H Kim; Gerald M Reaven
Journal:  Diabetes Care       Date:  2007-11-13       Impact factor: 19.112

8.  Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.

Authors:  Xiaocheng C Dong; Kyle D Copps; Shaodong Guo; Yedan Li; Ramya Kollipara; Ronald A DePinho; Morris F White
Journal:  Cell Metab       Date:  2008-07       Impact factor: 27.287

9.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.

Authors: 
Journal:  Lancet       Date:  1998-09-12       Impact factor: 79.321

Review 10.  Mouse models of insulin resistance.

Authors:  Anindita Nandi; Yukari Kitamura; C Ronald Kahn; Domenico Accili
Journal:  Physiol Rev       Date:  2004-04       Impact factor: 37.312
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  27 in total

1.  Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation.

Authors:  Li Qiang; Hua V Lin; Ja Young Kim-Muller; Carrie L Welch; Wei Gu; Domenico Accili
Journal:  Cell Metab       Date:  2011-11-10       Impact factor: 27.287

2.  Pathogenesis of selective insulin resistance in isolated hepatocytes.

Authors:  Joshua R Cook; Fanny Langlet; Yoshiaki Kido; Domenico Accili
Journal:  J Biol Chem       Date:  2015-04-14       Impact factor: 5.157

3.  Hoofbeats, zebras, and insights into insulin resistance.

Authors:  Robert A Hegele; Karen Reue
Journal:  J Clin Invest       Date:  2009-02       Impact factor: 14.808

4.  Proline oxidase-adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation.

Authors:  D Lettieri Barbato; K Aquilano; S Baldelli; S M Cannata; S Bernardini; G Rotilio; M R Ciriolo
Journal:  Cell Death Differ       Date:  2013-10-04       Impact factor: 15.828

5.  miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling.

Authors:  Alberto Dávalos; Leigh Goedeke; Peter Smibert; Cristina M Ramírez; Nikhil P Warrier; Ursula Andreo; Daniel Cirera-Salinas; Katey Rayner; Uthra Suresh; José Carlos Pastor-Pareja; Enric Esplugues; Edward A Fisher; Luiz O F Penalva; Kathryn J Moore; Yajaira Suárez; Eric C Lai; Carlos Fernández-Hernando
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-16       Impact factor: 11.205

6.  Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia.

Authors:  Rebecca A Haeusler; Seongah Han; Domenico Accili
Journal:  J Biol Chem       Date:  2010-06-23       Impact factor: 5.157

7.  Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity.

Authors:  Thomas A Bowman; Sadeesh K Ramakrishnan; Meenakshi Kaw; Sang Jun Lee; Payal R Patel; Varun K Golla; Raymond E Bourey; Per Magnus Haram; Lauren G Koch; Steven L Britton; Ulrik Wisløff; Abraham D Lee; Sonia M Najjar
Journal:  Endocrinology       Date:  2010-09-22       Impact factor: 4.736

Review 8.  Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models.

Authors:  Zhiyong Cheng; Morris F White
Journal:  Antioxid Redox Signal       Date:  2010-09-16       Impact factor: 8.401

9.  Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia.

Authors:  Rebecca A Haeusler; Matthew Pratt-Hyatt; Carrie L Welch; Curtis D Klaassen; Domenico Accili
Journal:  Cell Metab       Date:  2011-12-22       Impact factor: 27.287

10.  Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Authors:  Anke Assmann; Kohjiro Ueki; Jonathon N Winnay; Takahashi Kadowaki; Rohit N Kulkarni
Journal:  Mol Cell Biol       Date:  2009-03-09       Impact factor: 4.272
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