Literature DB >> 18590592

Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors.

Alison M Coates1, Stelios Sioutis, Jonathan D Buckley, Peter R C Howe.   

Abstract

The long-chain (LC) n-3 PUFA content of pork, particularly DHA, can be increased by including 15% PorcOmega (a fortified tuna fishmeal product) in pig finisher diets. The aim of the present study was to see whether this enriched pork could deliver cardiovascular health benefits to consumers. In a double-blind intervention trial, thirty-three healthy adult volunteers (sixteen female and seventeen male) were randomised to consume either n-3-enriched or regular (control) pork (a selection of five fresh cuts totalling 1000 g/week) for 12 weeks. Fasting blood samples were collected every 4 weeks and analysed for serum lipids, maximally stimulated thromboxane production and erythrocyte fatty acid composition. The n-3-enriched pork provided subjects with 1.3 g LC n-3 PUFA per week. Erythrocyte DHA levels rose 15% in the n-3 group and fell 5% in the control group over 12 weeks (P=0.001). Compared with the control group, serum TAG decreased to a greater extent in the n-3 group (P=0.02) and serum thromboxane production increased to a lesser extent (P=0.004). Changes in the latter were inversely associated with changes in incorporation of DHA into erythrocytes (r -0.54; P<0.05). Thus the modest increases in LC n-3 PUFA intake resulting from regular consumption of enriched pork can improve cardiovascular risk factors.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18590592     DOI: 10.1017/S0007114508025063

Source DB:  PubMed          Journal:  Br J Nutr        ISSN: 0007-1145            Impact factor:   3.718


  4 in total

Review 1.  A review of the effect of omega-3 polyunsaturated fatty acids on blood triacylglycerol levels in normolipidemic and borderline hyperlipidemic individuals.

Authors:  Michael A Leslie; Daniel J A Cohen; Danyelle M Liddle; Lindsay E Robinson; David W L Ma
Journal:  Lipids Health Dis       Date:  2015-06-06       Impact factor: 3.876

Review 2.  Pork as a Source of Omega-3 (n-3) Fatty Acids.

Authors:  Michael E R Dugan; Payam Vahmani; Tyler D Turner; Cletos Mapiye; Manuel Juárez; Nuria Prieto; Angela D Beaulieu; Ruurd T Zijlstra; John F Patience; Jennifer L Aalhus
Journal:  J Clin Med       Date:  2015-12-16       Impact factor: 4.241

3.  Effects of eating fresh lean pork on cardiometabolic health parameters.

Authors:  Karen J Murphy; Rebecca L Thomson; Alison M Coates; Jonathan D Buckley; Peter R C Howe
Journal:  Nutrients       Date:  2012-07-05       Impact factor: 5.717

4.  A comparison of regular consumption of fresh lean pork, beef and chicken on body composition: a randomized cross-over trial.

Authors:  Karen J Murphy; Barbara Parker; Kathryn A Dyer; Courtney R Davis; Alison M Coates; Jonathan D Buckley; Peter R C Howe
Journal:  Nutrients       Date:  2014-02-14       Impact factor: 5.717

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.