Literature DB >> 18590265

Prevalence of colorectal cancer and survival in patients from the Gampaha District, North Colombo region.

Thamara Perera1, Ruwan E Wijesuriya, P H R Suraweera, Kumudu Wijewardene, Sumudu K Kumarage, M H J Ariyaratne, Kemal I Deen.   

Abstract

INTRODUCTION: The prevalence and survival of colorectal cancer in Sri Lankans has not been previously reported. We did a retrospective and a prospective survey, in the region of North Colombo, Sri Lanka between 1992 and 2004. The aim was to study cancer burden, sites of colorectal cancer and survival after surgery. PATIENTS AND METHODS: The records of 175 patients with colorectal cancer between 1992 and 1997 in the selected region of were analysed retrospectively. A prospective study was performed in 220 new patients with colorectal cancer between 1996 and 2004. Data evaluated were demographics, tumour stage and survival.
RESULTS: Between 1992 and 1997 the crude annual incidence of colorectal cancer was 1.9 per 100,000, which increased over the years. The current national crude annual incidence is 3.2 per 100,000 in women and 4.9 in men. Median age at presentation was 60 years with similar prevalence of cancer in men and women. In the entire group, 28% of cancers were in those less than 50 years old. Survival at 2 and 5 years was 69% and 52%. The majority of cancer related deaths were within the first 2 years after surgery.
CONCLUSION: The burden of colorectal cancer in Sri Lanka is on the rise. Up to a third of cancers occur in those under 50 years, and the majority of cancers are in the rectum or rectosigmoid region. Flexible sigmoidoscopy offers a useful screening tool.

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Year:  2008        PMID: 18590265     DOI: 10.4038/cmj.v53i1.221

Source DB:  PubMed          Journal:  Ceylon Med J        ISSN: 0009-0875


  8 in total

1.  Proximal and distal rectal cancers differ in curative resectability and local recurrence.

Authors:  Wasantha Wijenayake; Mahendra Perera; Jayantha Balawardena; Raeed Deen; S Ruwan Wijesuriya; Sumudu K Kumarage; Kemal I Deen
Journal:  World J Gastrointest Surg       Date:  2011-08-27

2.  Characterization of germline mutations of MLH1 and MSH2 in unrelated south American suspected Lynch syndrome individuals.

Authors:  Mev Dominguez Valentin; Felipe Carneiro da Silva; Erika Maria Monteiro dos Santos; Bianca Garcia Lisboa; Ligia Petrolini de Oliveira; Fabio de Oliveira Ferreira; Israel Gomy; Wilson Toshihiko Nakagawa; Samuel Aguiar Junior; Mariana Redal; Carlos Vaccaro; Adriana Della Valle; Carlos Sarroca; Dirce Maria Carraro; Benedito Mauro Rossi
Journal:  Fam Cancer       Date:  2011-12       Impact factor: 2.375

3.  Disease characteristics of inflammatory bowel disease (IBD): findings from a tertiary care centre in South Asia.

Authors:  Duminda Subasinghe; N M M Nawarathna; Dharmabandhu Nandadeva Samarasekera
Journal:  J Gastrointest Surg       Date:  2011-06-28       Impact factor: 3.452

4.  Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: analysis of survival and prognostic markers.

Authors:  K K Chan; B Dassanayake; R Deen; R E Wickramarachchi; S K Kumarage; S Samita; K I Deen
Journal:  World J Surg Oncol       Date:  2010-09-15       Impact factor: 2.754

5.  Synchronous liver metastasis in colorectal cancer in Sri Lanka.

Authors:  Rohan Chaminda Siriwardana; S Ruwan E Wijesuriya; Sumudu K Kumarage; Kemal I Deen
Journal:  Indian J Gastroenterol       Date:  2010-08-26

6.  Estimating the incidence of colorectal cancer in South East Asia.

Authors:  Inka Kokki; Angeliki Papana; Harry Campbell; Evropi Theodoratou
Journal:  Croat Med J       Date:  2013-12       Impact factor: 1.351

7.  Colorectal cancer burden and trends in a South Asian cohort: experience from a regional tertiary care center in Sri Lanka.

Authors:  P C Chandrasinghe; D S Ediriweera; J Hewavisenthi; S K Kumarage; F R Fernando; K I Deen
Journal:  BMC Res Notes       Date:  2017-10-30

8.  Measuring quality in colorectal cancer surgery in low- and middle-income countries: The Clavien-Dindo classification in a Sri Lankan cohort.

Authors:  S Lindholm; S Lindskogen; B Gamage; G Kurlberg; D Ljungman
Journal:  Ann Med Surg (Lond)       Date:  2022-06-18
  8 in total

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