OBJECTIVE: To study chemical constituents of Changium smyrnioides Wolff. METHODS: The chemical components were isolated and purified by silica gel column and recrystallization. The chemical structures were elucidated on the basis of physico-chemical properties and spectral data. RESULTS: Ten compounds were isolated and identified as lignoceric acid (1), beta-sitosterol (2), stigmasterol (3), 5-hydroxy-8-methoxypsoralen (4), glycerylmonopalmitate (5), L-pyroglutamic acid (6), succinic acid (7), vanillic acid-4-O-beta-D-glucopyranoside (8 ), vanillic acid (9), daucosterol (10). CONCLUSION: Compounds 1, 4, 5, 6, 8 and 9 are obtained from the plant for the first time.
OBJECTIVE: To study chemical constituents of Changium smyrnioides Wolff. METHODS: The chemical components were isolated and purified by silica gel column and recrystallization. The chemical structures were elucidated on the basis of physico-chemical properties and spectral data. RESULTS: Ten compounds were isolated and identified as lignoceric acid (1), beta-sitosterol (2), stigmasterol (3), 5-hydroxy-8-methoxypsoralen (4), glycerylmonopalmitate (5), L-pyroglutamic acid (6), succinic acid (7), vanillic acid-4-O-beta-D-glucopyranoside (8 ), vanillic acid (9), daucosterol (10). CONCLUSION: Compounds 1, 4, 5, 6, 8 and 9 are obtained from the plant for the first time.